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Anti-CCL13/ CKb10/ MCP-4 functional antibody
Anti-CCL13/ CKb10/ MCP-4 functional antibody for cell culture, ELISA & in-vivo assay
Go to CCL13/CCL13 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0739-Ab-1/ GM-Tg-hg-SE0739-Ab-2 | Anti-Human CCL13 monoclonal antibody | Human |
| GM-Tg-rg-SE0739-Ab-1/ GM-Tg-rg-SE0739-Ab-2 | Anti-Rat CCL13 monoclonal antibody | Rat |
| GM-Tg-mg-SE0739-Ab-1/ GM-Tg-mg-SE0739-Ab-2 | Anti-Mouse CCL13 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0739-Ab-1/ GM-Tg-cynog-SE0739-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CCL13 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0739-Ab-1/ GM-Tg-felg-SE0739-Ab-2 | Anti-Feline CCL13 monoclonal antibody | Feline |
| GM-Tg-cang-SE0739-Ab-1/ GM-Tg-cang-SE0739-Ab-2 | Anti-Canine CCL13 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0739-Ab-1/ GM-Tg-bovg-SE0739-Ab-2 | Anti-Bovine CCL13 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0739-Ab-1/ GM-Tg-equg-SE0739-Ab-2 | Anti-Equine CCL13 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0739-Ab-1/ GM-Tg-hg-SE0739-Ab-2; GM-Tg-rg-SE0739-Ab-1/ GM-Tg-rg-SE0739-Ab-2; GM-Tg-mg-SE0739-Ab-1/ GM-Tg-mg-SE0739-Ab-2; GM-Tg-cynog-SE0739-Ab-1/ GM-Tg-cynog-SE0739-Ab-2; GM-Tg-felg-SE0739-Ab-1/ GM-Tg-felg-SE0739-Ab-2; GM-Tg-cang-SE0739-Ab-1/ GM-Tg-cang-SE0739-Ab-2; GM-Tg-bovg-SE0739-Ab-1/ GM-Tg-bovg-SE0739-Ab-2; GM-Tg-equg-SE0739-Ab-1/ GM-Tg-equg-SE0739-Ab-2 |
| Products Name | Anti-CCL13 monoclonal antibody |
| Format | mab |
| Target Name | CCL13 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CCL13 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0739-Ag-1 | Recombinant multi-species CCL13/ CKb10/ MCP-4 protein |
| Cytokine | GM-Tg-g-SE0739-Ag-1 | chemokine (C-C motif) ligand 13 (CCL13) protein |
| ORF Viral Vector | vGMLP002316 | human CCL13 Lentivirus particle |
| ORF Viral Vector | pGMLP002316 | human CCL13 Lentivirus plasmid |
Target information
| Target ID | GM-SE0739 |
| Target Name | CCL13 |
| Gene ID | 6357,714907 |
| Gene Symbol and Synonyms | CCL13,CKb10,MCP-4,NCC-1,NCC1,SCYA13,SCYL1 |
| Uniprot Accession | Q99616 |
| Uniprot Entry Name | CCL13_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Cytokine Target |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000181374 |
| Target Classification | N/A |
The target: CCL13, gene name: CCL13, also named as CKb10, MCP-4, NCC-1, NCC1, SCYA13, SCYL1. This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis. [provided by RefSeq, Sep 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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