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Anti-CCL7/ FIC/ MARC functional antibody
Anti-CCL7/ FIC/ MARC functional antibody for cell culture, ELISA & in-vivo assay
Go to CCL7/CCL7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0072-Ab-1/ GM-Tg-hg-SE0072-Ab-2 | Anti-Human CCL7 monoclonal antibody | Human |
| GM-Tg-rg-SE0072-Ab-1/ GM-Tg-rg-SE0072-Ab-2 | Anti-Rat CCL7 monoclonal antibody | Rat |
| GM-Tg-mg-SE0072-Ab-1/ GM-Tg-mg-SE0072-Ab-2 | Anti-Mouse CCL7 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0072-Ab-1/ GM-Tg-cynog-SE0072-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CCL7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0072-Ab-1/ GM-Tg-felg-SE0072-Ab-2 | Anti-Feline CCL7 monoclonal antibody | Feline |
| GM-Tg-cang-SE0072-Ab-1/ GM-Tg-cang-SE0072-Ab-2 | Anti-Canine CCL7 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0072-Ab-1/ GM-Tg-bovg-SE0072-Ab-2 | Anti-Bovine CCL7 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0072-Ab-1/ GM-Tg-equg-SE0072-Ab-2 | Anti-Equine CCL7 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0072-Ab-1/ GM-Tg-hg-SE0072-Ab-2; GM-Tg-rg-SE0072-Ab-1/ GM-Tg-rg-SE0072-Ab-2; GM-Tg-mg-SE0072-Ab-1/ GM-Tg-mg-SE0072-Ab-2; GM-Tg-cynog-SE0072-Ab-1/ GM-Tg-cynog-SE0072-Ab-2; GM-Tg-felg-SE0072-Ab-1/ GM-Tg-felg-SE0072-Ab-2; GM-Tg-cang-SE0072-Ab-1/ GM-Tg-cang-SE0072-Ab-2; GM-Tg-bovg-SE0072-Ab-1/ GM-Tg-bovg-SE0072-Ab-2; GM-Tg-equg-SE0072-Ab-1/ GM-Tg-equg-SE0072-Ab-2 |
| Products Name | Anti-CCL7 monoclonal antibody |
| Format | mab |
| Target Name | CCL7 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CCL7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0072-Ag-1 | Recombinant multi-species CCL7/ FIC/ MARC protein |
| Cytokine | GM-Tg-g-SE0072-Ag-1 | chemokine (C-C motif) ligand 7 (CCL7) protein |
| ORF Viral Vector | pGMLP000252 | human CCL7 Lentivirus plasmid |
| ORF Viral Vector | vGMLP000252 | human CCL7 Lentivirus particle |
| ORF Viral Vector | pGMLPm000874 | mouse Ccl7 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000874 | mouse Ccl7 Lentivirus particle |
Target information
| Target ID | GM-SE0072 |
| Target Name | CCL7 |
| Gene ID | 6354,714751 |
| Gene Symbol and Synonyms | CCL7,FIC,MARC,MCP-3,MCP3,NC28,SCYA6,SCYA7 |
| Uniprot Accession | P80098 |
| Uniprot Entry Name | CCL7_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000108688 |
| Target Classification | N/A |
The target: CCL7, gene name: CCL7, also named as FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7. This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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