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Anti-CCL24/ Ckb-6/ MPIF-2 functional antibody
Anti-CCL24/ Ckb-6/ MPIF-2 functional antibody for cell culture, ELISA & in-vivo assay
Go to CCL24/CCL24 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0070-Ab-1/ GM-Tg-hg-SE0070-Ab-2 | Anti-Human CCL24 monoclonal antibody | Human |
| GM-Tg-rg-SE0070-Ab-1/ GM-Tg-rg-SE0070-Ab-2 | Anti-Rat CCL24 monoclonal antibody | Rat |
| GM-Tg-mg-SE0070-Ab-1/ GM-Tg-mg-SE0070-Ab-2 | Anti-Mouse CCL24 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0070-Ab-1/ GM-Tg-cynog-SE0070-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CCL24 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0070-Ab-1/ GM-Tg-felg-SE0070-Ab-2 | Anti-Feline CCL24 monoclonal antibody | Feline |
| GM-Tg-cang-SE0070-Ab-1/ GM-Tg-cang-SE0070-Ab-2 | Anti-Canine CCL24 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0070-Ab-1/ GM-Tg-bovg-SE0070-Ab-2 | Anti-Bovine CCL24 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0070-Ab-1/ GM-Tg-equg-SE0070-Ab-2 | Anti-Equine CCL24 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0070-Ab-1/ GM-Tg-hg-SE0070-Ab-2; GM-Tg-rg-SE0070-Ab-1/ GM-Tg-rg-SE0070-Ab-2; GM-Tg-mg-SE0070-Ab-1/ GM-Tg-mg-SE0070-Ab-2; GM-Tg-cynog-SE0070-Ab-1/ GM-Tg-cynog-SE0070-Ab-2; GM-Tg-felg-SE0070-Ab-1/ GM-Tg-felg-SE0070-Ab-2; GM-Tg-cang-SE0070-Ab-1/ GM-Tg-cang-SE0070-Ab-2; GM-Tg-bovg-SE0070-Ab-1/ GM-Tg-bovg-SE0070-Ab-2; GM-Tg-equg-SE0070-Ab-1/ GM-Tg-equg-SE0070-Ab-2 |
| Products Name | Anti-CCL24 monoclonal antibody |
| Format | mab |
| Target Name | CCL24 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CCL24 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0070-Ag-1 | Recombinant multi-species CCL24/ Ckb-6/ MPIF-2 protein |
| Cytokine | GM-Tg-g-SE0070-Ag-1 | chemokine (C-C motif) ligand 24 (CCL24) protein |
| ORF Viral Vector | pGMLP003812 | human CCL24 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003812 | human CCL24 Lentivirus particle |
Target information
| Target ID | GM-SE0070 |
| Target Name | CCL24 |
| Gene ID | 6369,56221,288593,716050,445452,101086275,617258,100061208 |
| Gene Symbol and Synonyms | CCL24,Ckb-6,MPIF-2,MPIF2,SCYA24 |
| Uniprot Accession | O00175,Q68Y86 |
| Uniprot Entry Name | CCL24_HUMAN,CCL24_CANLF |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000106178 |
| Target Classification | N/A |
The target: CCL24, gene name: CCL24, also named as Ckb-6, MPIF-2, MPIF2, SCYA24. This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. This protein also has antimicrobial activity, displaying an antibacterial effect on S. pneumoniae, S. aureus, Non-typeable H. influenzae, and P. aeruginosa. Finally, the protein is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. [provided by RefSeq, Jul 2020].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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