Anti-RB27B/ RAB27B/ C25KG monoclonal antibody

Anti-RB27B/ RAB27B/ C25KG antibody for FACS & in-vivo assay

Target products collectionGo to RAB27B/RAB27B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2275-Ab-1/ GM-Tg-hg-MP2275-Ab-2Anti-Human RAB27B monoclonal antibodyHuman
GM-Tg-rg-MP2275-Ab-1/ GM-Tg-rg-MP2275-Ab-2Anti-Rat RAB27B monoclonal antibodyRat
GM-Tg-mg-MP2275-Ab-1/ GM-Tg-mg-MP2275-Ab-2Anti-Mouse RAB27B monoclonal antibodyMouse
GM-Tg-cynog-MP2275-Ab-1/ GM-Tg-cynog-MP2275-Ab-2Anti-Cynomolgus/ Rhesus macaque RAB27B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2275-Ab-1/ GM-Tg-felg-MP2275-Ab-2Anti-Feline RAB27B monoclonal antibodyFeline
GM-Tg-cang-MP2275-Ab-1/ GM-Tg-cang-MP2275-Ab-2Anti-Canine RAB27B monoclonal antibodyCanine
GM-Tg-bovg-MP2275-Ab-1/ GM-Tg-bovg-MP2275-Ab-2Anti-Bovine RAB27B monoclonal antibodyBovine
GM-Tg-equg-MP2275-Ab-1/ GM-Tg-equg-MP2275-Ab-2Anti-Equine RAB27B monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2275-Ab-1/ GM-Tg-hg-MP2275-Ab-2; GM-Tg-rg-MP2275-Ab-1/ GM-Tg-rg-MP2275-Ab-2;
GM-Tg-mg-MP2275-Ab-1/ GM-Tg-mg-MP2275-Ab-2; GM-Tg-cynog-MP2275-Ab-1/ GM-Tg-cynog-MP2275-Ab-2;
GM-Tg-felg-MP2275-Ab-1/ GM-Tg-felg-MP2275-Ab-2; GM-Tg-cang-MP2275-Ab-1/ GM-Tg-cang-MP2275-Ab-2;
GM-Tg-bovg-MP2275-Ab-1/ GM-Tg-bovg-MP2275-Ab-2; GM-Tg-equg-MP2275-Ab-1/ GM-Tg-equg-MP2275-Ab-2
Products NameAnti-RAB27B monoclonal antibody
Formatmab
Target NameRAB27B
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-RAB27B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species RB27B/ RAB27B/ C25KG VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP002172human RAB27B Lentivirus particle
    ORF Viral VectorpGMLP002172human RAB27B Lentivirus plasmid
    ORF Viral VectorpGMLPm000430mouse Rab27b Lentivirus plasmid
    ORF Viral VectorvGMLPm000430mouse Rab27b Lentivirus particle


    Target information

    Target IDGM-MP2275
    Target NameRAB27B
    Gene ID5874,80718,84590,694445,483974,101096852,282858,100049861
    Gene Symbol and Synonyms2310021G14Rik,B130064M09Rik,C25KG,RAB27B
    Uniprot AccessionO00194,Q99P74,Q8HZJ5
    Uniprot Entry NameRB27B_HUMAN,RB27B_RAT,RB27B_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000041353
    Target ClassificationN/A

    The target: RAB27B, gene name: RAB27B, also named as C25KG. Members of the Rab protein family, including RAB27B, are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking (Chen et al., 1997 [PubMed 9066979]).[supplied by OMIM, Nov 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.