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Anti-SDCB1/ SDCBP/ MDA-9 monoclonal antibody
Anti-SDCB1/ SDCBP/ MDA-9 antibody for FACS & in-vivo assay
Go to SDCBP/SDCBP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1494-Ab-1/ GM-Tg-hg-MP1494-Ab-2 | Anti-Human SDCBP monoclonal antibody | Human |
| GM-Tg-rg-MP1494-Ab-1/ GM-Tg-rg-MP1494-Ab-2 | Anti-Rat SDCBP monoclonal antibody | Rat |
| GM-Tg-mg-MP1494-Ab-1/ GM-Tg-mg-MP1494-Ab-2 | Anti-Mouse SDCBP monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1494-Ab-1/ GM-Tg-cynog-MP1494-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SDCBP monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1494-Ab-1/ GM-Tg-felg-MP1494-Ab-2 | Anti-Feline SDCBP monoclonal antibody | Feline |
| GM-Tg-cang-MP1494-Ab-1/ GM-Tg-cang-MP1494-Ab-2 | Anti-Canine SDCBP monoclonal antibody | Canine |
| GM-Tg-bovg-MP1494-Ab-1/ GM-Tg-bovg-MP1494-Ab-2 | Anti-Bovine SDCBP monoclonal antibody | Bovine |
| GM-Tg-equg-MP1494-Ab-1/ GM-Tg-equg-MP1494-Ab-2 | Anti-Equine SDCBP monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1494-Ab-1/ GM-Tg-hg-MP1494-Ab-2; GM-Tg-rg-MP1494-Ab-1/ GM-Tg-rg-MP1494-Ab-2; GM-Tg-mg-MP1494-Ab-1/ GM-Tg-mg-MP1494-Ab-2; GM-Tg-cynog-MP1494-Ab-1/ GM-Tg-cynog-MP1494-Ab-2; GM-Tg-felg-MP1494-Ab-1/ GM-Tg-felg-MP1494-Ab-2; GM-Tg-cang-MP1494-Ab-1/ GM-Tg-cang-MP1494-Ab-2; GM-Tg-bovg-MP1494-Ab-1/ GM-Tg-bovg-MP1494-Ab-2; GM-Tg-equg-MP1494-Ab-1/ GM-Tg-equg-MP1494-Ab-2 |
| Products Name | Anti-SDCBP monoclonal antibody |
| Format | mab |
| Target Name | SDCBP |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SDCBP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species SDCB1/ SDCBP/ MDA-9 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP001007 | human SDCBP Lentivirus particle |
| ORF Viral Vector | pGMLP001008 | human SDCBP Lentivirus plasmid |
| ORF Viral Vector | vGMLP001008 | human SDCBP Lentivirus particle |
| ORF Viral Vector | pGMLP001007 | human SDCBP Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001135 | mouse Sdcbp Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001135 | mouse Sdcbp Lentivirus particle |
Target information
| Target ID | GM-MP1494 |
| Target Name | SDCBP |
| Gene ID | 6386,53378,83841,698381,482977,101099858,510979,100052836 |
| Gene Symbol and Synonyms | MDA-9,MDA9,SDCBP,ST1,SYCL,syntenin-1,TACIP18 |
| Uniprot Accession | O00560,Q9JI92 |
| Uniprot Entry Name | SDCB1_HUMAN,SDCB1_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Renal cell carcinoma |
| Gene Ensembl | ENSG00000137575 |
| Target Classification | N/A |
The target: SDCBP, gene name: SDCBP, also named as MDA-9, MDA9, ST1, SYCL, TACIP18. The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms. Related pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Jan 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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