Anti-MGST1/ GST12/ MGST monoclonal antibody

Anti-MGST1/ GST12/ MGST antibody for FACS & in-vivo assay

Target products collectionGo to MGST1/MGST1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0811-Ab-1/ GM-Tg-hg-MP0811-Ab-2Anti-Human MGST1 monoclonal antibodyHuman
GM-Tg-rg-MP0811-Ab-1/ GM-Tg-rg-MP0811-Ab-2Anti-Rat MGST1 monoclonal antibodyRat
GM-Tg-mg-MP0811-Ab-1/ GM-Tg-mg-MP0811-Ab-2Anti-Mouse MGST1 monoclonal antibodyMouse
GM-Tg-cynog-MP0811-Ab-1/ GM-Tg-cynog-MP0811-Ab-2Anti-Cynomolgus/ Rhesus macaque MGST1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0811-Ab-1/ GM-Tg-felg-MP0811-Ab-2Anti-Feline MGST1 monoclonal antibodyFeline
GM-Tg-cang-MP0811-Ab-1/ GM-Tg-cang-MP0811-Ab-2Anti-Canine MGST1 monoclonal antibodyCanine
GM-Tg-bovg-MP0811-Ab-1/ GM-Tg-bovg-MP0811-Ab-2Anti-Bovine MGST1 monoclonal antibodyBovine
GM-Tg-equg-MP0811-Ab-1/ GM-Tg-equg-MP0811-Ab-2Anti-Equine MGST1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0811-Ab-1/ GM-Tg-hg-MP0811-Ab-2; GM-Tg-rg-MP0811-Ab-1/ GM-Tg-rg-MP0811-Ab-2;
GM-Tg-mg-MP0811-Ab-1/ GM-Tg-mg-MP0811-Ab-2; GM-Tg-cynog-MP0811-Ab-1/ GM-Tg-cynog-MP0811-Ab-2;
GM-Tg-felg-MP0811-Ab-1/ GM-Tg-felg-MP0811-Ab-2; GM-Tg-cang-MP0811-Ab-1/ GM-Tg-cang-MP0811-Ab-2;
GM-Tg-bovg-MP0811-Ab-1/ GM-Tg-bovg-MP0811-Ab-2; GM-Tg-equg-MP0811-Ab-1/ GM-Tg-equg-MP0811-Ab-2
Products NameAnti-MGST1 monoclonal antibody
Formatmab
Target NameMGST1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MGST1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MGST1/ GST12/ MGST VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP000892human MGST1 Lentivirus plasmid
    ORF Viral VectorvGMLP000892human MGST1 Lentivirus particle
    ORF Viral VectorpGMLPm000923mouse Mgst1 Lentivirus plasmid
    ORF Viral VectorvGMLPm000923mouse Mgst1 Lentivirus particle


    Target information

    Target IDGM-MP0811
    Target NameMGST1
    Gene ID4257,56615,171341,701652,477683,101099565,493719,100064102
    Gene Symbol and Synonyms1500002K10Rik,Gst,GST12,MGST,MGST-I,MGST1,PMAN
    Uniprot AccessionP10620,P08011,Q64L89
    Uniprot Entry NameMGST1_HUMAN,MGST1_RAT,MGST1_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseLung Cancer
    Gene EnsemblENSG00000008394
    Target ClassificationN/A

    The target: MGST1, gene name: MGST1, also named as GST12, MGST, MGST-I. The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene. [provided by RefSeq, May 2012].



    About Gmab

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    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.