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Anti-CEAM7/ CEACAM7/ CGM2 monoclonal antibody
Anti-CEAM7/ CEACAM7/ CGM2 antibody for FACS & in-vivo assay
Go to CEACAM7/CEACAM7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0249-Ab-1/ GM-Tg-hg-MP0249-Ab-2 | Anti-Human CEACAM7 monoclonal antibody | Human |
| GM-Tg-rg-MP0249-Ab-1/ GM-Tg-rg-MP0249-Ab-2 | Anti-Rat CEACAM7 monoclonal antibody | Rat |
| GM-Tg-mg-MP0249-Ab-1/ GM-Tg-mg-MP0249-Ab-2 | Anti-Mouse CEACAM7 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0249-Ab-1/ GM-Tg-cynog-MP0249-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CEACAM7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0249-Ab-1/ GM-Tg-felg-MP0249-Ab-2 | Anti-Feline CEACAM7 monoclonal antibody | Feline |
| GM-Tg-cang-MP0249-Ab-1/ GM-Tg-cang-MP0249-Ab-2 | Anti-Canine CEACAM7 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0249-Ab-1/ GM-Tg-bovg-MP0249-Ab-2 | Anti-Bovine CEACAM7 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0249-Ab-1/ GM-Tg-equg-MP0249-Ab-2 | Anti-Equine CEACAM7 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0249-Ab-1/ GM-Tg-hg-MP0249-Ab-2; GM-Tg-rg-MP0249-Ab-1/ GM-Tg-rg-MP0249-Ab-2; GM-Tg-mg-MP0249-Ab-1/ GM-Tg-mg-MP0249-Ab-2; GM-Tg-cynog-MP0249-Ab-1/ GM-Tg-cynog-MP0249-Ab-2; GM-Tg-felg-MP0249-Ab-1/ GM-Tg-felg-MP0249-Ab-2; GM-Tg-cang-MP0249-Ab-1/ GM-Tg-cang-MP0249-Ab-2; GM-Tg-bovg-MP0249-Ab-1/ GM-Tg-bovg-MP0249-Ab-2; GM-Tg-equg-MP0249-Ab-1/ GM-Tg-equg-MP0249-Ab-2 |
| Products Name | Anti-CEACAM7 monoclonal antibody |
| Format | mab |
| Target Name | CEACAM7 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CEACAM7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species CEAM7/ CEACAM7/ CGM2 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP002341 | human CEACAM7 Lentivirus particle |
| ORF Viral Vector | pGMLP002341 | human CEACAM7 Lentivirus plasmid |
Target information
| Target ID | GM-MP0249 |
| Target Name | CEACAM7 |
| Gene ID | 1087,705572 |
| Gene Symbol and Synonyms | CEACAM7,CGM2 |
| Uniprot Accession | Q14002 |
| Uniprot Entry Name | CEAM7_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000007306 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: CEACAM7, gene name: CEACAM7, also named as CGM2. This gene encodes a cell surface glycoprotein and member of the carcinoembryonic antigen (CEA) family of proteins. Expression of this gene may be downregulated in colon and rectal cancer. Additionally, lower expression levels of this gene may be predictive of rectal cancer recurrence. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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