Anti-CABP8/ CALN1 monoclonal antibody
Anti-CABP8/ CALN1 antibody for FACS & in-vivo assay
Go to CALN1/CALN1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-MP0177-Ab-1/ GM-Tg-hg-MP0177-Ab-2 | Anti-Human CALN1 monoclonal antibody | Human |
GM-Tg-rg-MP0177-Ab-1/ GM-Tg-rg-MP0177-Ab-2 | Anti-Rat CALN1 monoclonal antibody | Rat |
GM-Tg-mg-MP0177-Ab-1/ GM-Tg-mg-MP0177-Ab-2 | Anti-Mouse CALN1 monoclonal antibody | Mouse |
GM-Tg-cynog-MP0177-Ab-1/ GM-Tg-cynog-MP0177-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CALN1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-MP0177-Ab-1/ GM-Tg-felg-MP0177-Ab-2 | Anti-Feline CALN1 monoclonal antibody | Feline |
GM-Tg-cang-MP0177-Ab-1/ GM-Tg-cang-MP0177-Ab-2 | Anti-Canine CALN1 monoclonal antibody | Canine |
GM-Tg-bovg-MP0177-Ab-1/ GM-Tg-bovg-MP0177-Ab-2 | Anti-Bovine CALN1 monoclonal antibody | Bovine |
GM-Tg-equg-MP0177-Ab-1/ GM-Tg-equg-MP0177-Ab-2 | Anti-Equine CALN1 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-MP0177-Ab-1/ GM-Tg-hg-MP0177-Ab-2; GM-Tg-rg-MP0177-Ab-1/ GM-Tg-rg-MP0177-Ab-2; GM-Tg-mg-MP0177-Ab-1/ GM-Tg-mg-MP0177-Ab-2; GM-Tg-cynog-MP0177-Ab-1/ GM-Tg-cynog-MP0177-Ab-2; GM-Tg-felg-MP0177-Ab-1/ GM-Tg-felg-MP0177-Ab-2; GM-Tg-cang-MP0177-Ab-1/ GM-Tg-cang-MP0177-Ab-2; GM-Tg-bovg-MP0177-Ab-1/ GM-Tg-bovg-MP0177-Ab-2; GM-Tg-equg-MP0177-Ab-1/ GM-Tg-equg-MP0177-Ab-2 |
Products Name | Anti-CALN1 monoclonal antibody |
Format | mab |
Target Name | CALN1 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-CALN1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species CABP8/ CALN1 VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | vGMLP004455 | human CALN1 Lentivirus particle |
ORF Viral Vector | pGMLP004455 | human CALN1 Lentivirus plasmid |
ORF Viral Vector | pGMLPm000345 | mouse Caln1 Lentivirus plasmid |
ORF Viral Vector | vGMLPm000345 | mouse Caln1 Lentivirus particle |
Target information
Target ID | GM-MP0177 |
Target Name | CALN1 |
Gene ID | 83698,140904,363909,695315,607123,101100355,538163,100062180 |
Gene Symbol and Synonyms | 9630012C17Rik,CABP8,CALN1,MNCb-0849 |
Uniprot Accession | Q9BXU9,Q06BI3 |
Uniprot Entry Name | CABP8_HUMAN,CABP8_RAT |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000183166 |
Target Classification | N/A |
The target: CALN1, gene name: CALN1, also named as CABP8. This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.