Anti-CABP8/ CALN1 monoclonal antibody

Anti-CABP8/ CALN1 antibody for FACS & in-vivo assay

Target products collectionGo to CALN1/CALN1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0177-Ab-1/ GM-Tg-hg-MP0177-Ab-2Anti-Human CALN1 monoclonal antibodyHuman
GM-Tg-rg-MP0177-Ab-1/ GM-Tg-rg-MP0177-Ab-2Anti-Rat CALN1 monoclonal antibodyRat
GM-Tg-mg-MP0177-Ab-1/ GM-Tg-mg-MP0177-Ab-2Anti-Mouse CALN1 monoclonal antibodyMouse
GM-Tg-cynog-MP0177-Ab-1/ GM-Tg-cynog-MP0177-Ab-2Anti-Cynomolgus/ Rhesus macaque CALN1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0177-Ab-1/ GM-Tg-felg-MP0177-Ab-2Anti-Feline CALN1 monoclonal antibodyFeline
GM-Tg-cang-MP0177-Ab-1/ GM-Tg-cang-MP0177-Ab-2Anti-Canine CALN1 monoclonal antibodyCanine
GM-Tg-bovg-MP0177-Ab-1/ GM-Tg-bovg-MP0177-Ab-2Anti-Bovine CALN1 monoclonal antibodyBovine
GM-Tg-equg-MP0177-Ab-1/ GM-Tg-equg-MP0177-Ab-2Anti-Equine CALN1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0177-Ab-1/ GM-Tg-hg-MP0177-Ab-2; GM-Tg-rg-MP0177-Ab-1/ GM-Tg-rg-MP0177-Ab-2;
GM-Tg-mg-MP0177-Ab-1/ GM-Tg-mg-MP0177-Ab-2; GM-Tg-cynog-MP0177-Ab-1/ GM-Tg-cynog-MP0177-Ab-2;
GM-Tg-felg-MP0177-Ab-1/ GM-Tg-felg-MP0177-Ab-2; GM-Tg-cang-MP0177-Ab-1/ GM-Tg-cang-MP0177-Ab-2;
GM-Tg-bovg-MP0177-Ab-1/ GM-Tg-bovg-MP0177-Ab-2; GM-Tg-equg-MP0177-Ab-1/ GM-Tg-equg-MP0177-Ab-2
Products NameAnti-CALN1 monoclonal antibody
Formatmab
Target NameCALN1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CALN1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CABP8/ CALN1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP004455human CALN1 Lentivirus particle
    ORF Viral VectorpGMLP004455human CALN1 Lentivirus plasmid
    ORF Viral VectorpGMLPm000345mouse Caln1 Lentivirus plasmid
    ORF Viral VectorvGMLPm000345mouse Caln1 Lentivirus particle


    Target information

    Target IDGM-MP0177
    Target NameCALN1
    Gene ID83698,140904,363909,695315,607123,101100355,538163,100062180
    Gene Symbol and Synonyms9630012C17Rik,CABP8,CALN1,MNCb-0849
    Uniprot AccessionQ9BXU9,Q06BI3
    Uniprot Entry NameCABP8_HUMAN,CABP8_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000183166
    Target ClassificationN/A

    The target: CALN1, gene name: CALN1, also named as CABP8. This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.