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Anti-AQP6/ AQP2L/ KID monoclonal antibody
Anti-AQP6/ AQP2L/ KID antibody for FACS & in-vivo assay
Go to AQP6/AQP6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0082-Ab-1/ GM-Tg-hg-MP0082-Ab-2 | Anti-Human AQP6 monoclonal antibody | Human |
| GM-Tg-rg-MP0082-Ab-1/ GM-Tg-rg-MP0082-Ab-2 | Anti-Rat AQP6 monoclonal antibody | Rat |
| GM-Tg-mg-MP0082-Ab-1/ GM-Tg-mg-MP0082-Ab-2 | Anti-Mouse AQP6 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0082-Ab-1/ GM-Tg-cynog-MP0082-Ab-2 | Anti-Cynomolgus/ Rhesus macaque AQP6 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0082-Ab-1/ GM-Tg-felg-MP0082-Ab-2 | Anti-Feline AQP6 monoclonal antibody | Feline |
| GM-Tg-cang-MP0082-Ab-1/ GM-Tg-cang-MP0082-Ab-2 | Anti-Canine AQP6 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0082-Ab-1/ GM-Tg-bovg-MP0082-Ab-2 | Anti-Bovine AQP6 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0082-Ab-1/ GM-Tg-equg-MP0082-Ab-2 | Anti-Equine AQP6 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0082-Ab-1/ GM-Tg-hg-MP0082-Ab-2; GM-Tg-rg-MP0082-Ab-1/ GM-Tg-rg-MP0082-Ab-2; GM-Tg-mg-MP0082-Ab-1/ GM-Tg-mg-MP0082-Ab-2; GM-Tg-cynog-MP0082-Ab-1/ GM-Tg-cynog-MP0082-Ab-2; GM-Tg-felg-MP0082-Ab-1/ GM-Tg-felg-MP0082-Ab-2; GM-Tg-cang-MP0082-Ab-1/ GM-Tg-cang-MP0082-Ab-2; GM-Tg-bovg-MP0082-Ab-1/ GM-Tg-bovg-MP0082-Ab-2; GM-Tg-equg-MP0082-Ab-1/ GM-Tg-equg-MP0082-Ab-2 |
| Products Name | Anti-AQP6 monoclonal antibody |
| Format | mab |
| Target Name | AQP6 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-AQP6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species AQP6/ AQP2L/ KID VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP004738 | human KID Lentivirus plasmid |
| ORF Viral Vector | vGMLP004738 | human KID Lentivirus particle |
Target information
| Target ID | GM-MP0082 |
| Target Name | AQP6 |
| Gene ID | 363,11831,29170,711968,607978,101093446,527759,100629869 |
| Gene Symbol and Synonyms | AQP2L,AQP6,KID |
| Uniprot Accession | Q13520,Q9WTY0 |
| Uniprot Entry Name | AQP6_HUMAN,AQP6_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000086159 |
| Target Classification | N/A |
The target: AQP6, gene name: AQP6, also named as AQP2L, KID. The protein encoded by this gene is an aquaporin protein, which functions as a water channel in cells. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This protein is specific for the kidney. This gene and related family members AQP0, AQP2, and AQP5 reside in a cluster on chromosome 12q13. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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