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Anti-BCAP31 monoclonal antibody
Pre-made anti-BCAP31 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to BCAP31/BCAP31 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0414-Ab-1/ GM-Tg-hg-IP0414-Ab-2 | Anti-Human BCAP31 monoclonal antibody | Human |
| GM-Tg-rg-IP0414-Ab-1/ GM-Tg-rg-IP0414-Ab-2 | Anti-Rat BCAP31 monoclonal antibody | Rat |
| GM-Tg-mg-IP0414-Ab-1/ GM-Tg-mg-IP0414-Ab-2 | Anti-Mouse BCAP31 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0414-Ab-1/ GM-Tg-cynog-IP0414-Ab-2 | Anti-Cynomolgus/ Rhesus macaque BCAP31 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0414-Ab-1/ GM-Tg-felg-IP0414-Ab-2 | Anti-Feline BCAP31 monoclonal antibody | Feline |
| GM-Tg-cang-IP0414-Ab-1/ GM-Tg-cang-IP0414-Ab-2 | Anti-Canine BCAP31 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0414-Ab-1/ GM-Tg-bovg-IP0414-Ab-2 | Anti-Bovine BCAP31 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0414-Ab-1/ GM-Tg-equg-IP0414-Ab-2 | Anti-Equine BCAP31 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0414-Ab-1/ GM-Tg-hg-IP0414-Ab-2; GM-Tg-rg-IP0414-Ab-1/ GM-Tg-rg-IP0414-Ab-2; GM-Tg-mg-IP0414-Ab-1/ GM-Tg-mg-IP0414-Ab-2; GM-Tg-cynog-IP0414-Ab-1/ GM-Tg-cynog-IP0414-Ab-2; GM-Tg-felg-IP0414-Ab-1/ GM-Tg-felg-IP0414-Ab-2; GM-Tg-cang-IP0414-Ab-1/ GM-Tg-cang-IP0414-Ab-2; GM-Tg-bovg-IP0414-Ab-1/ GM-Tg-bovg-IP0414-Ab-2; GM-Tg-equg-IP0414-Ab-1/ GM-Tg-equg-IP0414-Ab-2 |
| Products Name | Anti-BCAP31 monoclonal antibody |
| Format | mab |
| Target Name | BCAP31 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-BCAP31 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0414-Ag-1 | Recombinant multi-species BAP31/ BCAP31/ 6C6-AG protein |
| ORF Viral Vector | pGMLP004845 | human BCAP31 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000207 | human BCAP31 Lentivirus particle |
| ORF Viral Vector | pGMLV000207 | human BCAP31 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004845 | human BCAP31 Lentivirus particle |
| ORF Viral Vector | pGMLPm000801 | mouse Bcap31 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000801 | mouse Bcap31 Lentivirus particle |
Target information
| Target ID | GM-IP0414 |
| Target Name | BCAP31 |
| Gene ID | 10134,27061,293852,696663,481080,101081202,533949,100058834 |
| Gene Symbol and Synonyms | 6C6-AG,BAP31,BCAP31,CDM,DDCH,DELXQ28,DXS1357E,MICRODELXq28 |
| Uniprot Accession | P51572 |
| Uniprot Entry Name | BAP31_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000185825 |
| Target Classification | N/A |
The target: BCAP31, gene name: BCAP31, also named as 6C6-AG, BAP31, CDM, DDCH, DXS1357E. This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16. [provided by RefSeq, Jan 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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