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Anti-TNK1 monoclonal antibody
Pre-made anti-TNK1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to TNK1/TNK1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP0190-Ab-1/ GM-Tg-hg-IP0190-Ab-2 | Anti-Human TNK1 monoclonal antibody | Human |
| GM-Tg-rg-IP0190-Ab-1/ GM-Tg-rg-IP0190-Ab-2 | Anti-Rat TNK1 monoclonal antibody | Rat |
| GM-Tg-mg-IP0190-Ab-1/ GM-Tg-mg-IP0190-Ab-2 | Anti-Mouse TNK1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP0190-Ab-1/ GM-Tg-cynog-IP0190-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TNK1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP0190-Ab-1/ GM-Tg-felg-IP0190-Ab-2 | Anti-Feline TNK1 monoclonal antibody | Feline |
| GM-Tg-cang-IP0190-Ab-1/ GM-Tg-cang-IP0190-Ab-2 | Anti-Canine TNK1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP0190-Ab-1/ GM-Tg-bovg-IP0190-Ab-2 | Anti-Bovine TNK1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP0190-Ab-1/ GM-Tg-equg-IP0190-Ab-2 | Anti-Equine TNK1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP0190-Ab-1/ GM-Tg-hg-IP0190-Ab-2; GM-Tg-rg-IP0190-Ab-1/ GM-Tg-rg-IP0190-Ab-2; GM-Tg-mg-IP0190-Ab-1/ GM-Tg-mg-IP0190-Ab-2; GM-Tg-cynog-IP0190-Ab-1/ GM-Tg-cynog-IP0190-Ab-2; GM-Tg-felg-IP0190-Ab-1/ GM-Tg-felg-IP0190-Ab-2; GM-Tg-cang-IP0190-Ab-1/ GM-Tg-cang-IP0190-Ab-2; GM-Tg-bovg-IP0190-Ab-1/ GM-Tg-bovg-IP0190-Ab-2; GM-Tg-equg-IP0190-Ab-1/ GM-Tg-equg-IP0190-Ab-2 |
| Products Name | Anti-TNK1 monoclonal antibody |
| Format | mab |
| Target Name | TNK1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-TNK1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP0190-Ag-1 | Recombinant multi-species TNK1 protein |
| ORF Viral Vector | pGMLP004347 | human TNK1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004347 | human TNK1 Lentivirus particle |
| ORF Viral Vector | pGMLPm004735 | mouse Tnk1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004735 | mouse Tnk1 Lentivirus particle |
Target information
| Target ID | GM-IP0190 |
| Target Name | TNK1 |
| Gene ID | 8711,83813,303247,715180,489470,101096181,510356,100061776 |
| Gene Symbol and Synonyms | Ack-like,KOS1,TNK1,Tnk1a,Tnk1b |
| Uniprot Accession | Q13470 |
| Uniprot Entry Name | TNK1_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000174292 |
| Target Classification | Kinase |
The target: TNK1, gene name: TNK1, also named as . The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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