Human TNK1 ORF/cDNA clone-Lentivirus plasmid (NM_001251902)

SKU: pGMLP004347
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human TNK1/ Lentiviral expression plasmid for TNK1 lentivirus packaging, TNK1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP004347
Gene Name TNK1
Accession Number NM_001251902
Gene ID 8711
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 2001 bp
Gene Alias
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
Sequence ATGCTTCCTGAGGCTGGCTCCCTGTGGCTACTGAAGCTGCTCCGGGACATCCAGTTGGCCCAGTTTTACTGGCCCATCCTTGAGGAGCTTAATGTCACTCGGCCAGAGCACTTCGACTTTGTAAAGCCTGAGGACCTGGACGGCATTGGCATGGGCCGGCCTGCCCAGCGCAGACTGTCCGAAGCTCTGAAAAGGCTACGTTCTGGGCCTAAGTCTAAGAACTGGGTCTACAAGATCCTTGGAGGTTTTGCCCCTGAGCACAAGGAGCCCACCCTGCCCTCGGACAGCCCACGGCACCTCCCTGAGCCAGAGGGGGGCCTCAAGTGTCTGATCCCAGAGGGTGCTGTTTGCAGAGGGGAGCTGCTGGGTTCAGGCTGCTTCGGTGTGGTGCACCGAGGGCTGTGGACGCTGCCCAGTGGCAAGAGTGTCCCAGTGGCTGTCAAGTCCCTCCGGGTAGGTCCCGAAGGCCCGATGGGCACAGAACTGGGGGACTTCCTGCGAGAGGTATCGGTCATGATGAACTTGGAGCACCCACACGTGCTGCGTCTGCACGGCCTTGTACTGGGCCAGCCTCTGCAGATGGTGATGGAGCTGGCGCCACTGGGCTCCCTGCACGCGCGCCTAACGGCCCCGGCCCCGACACCCCCGCTGCTCGTGGCCCTGCTCTGCCTCTTCCTGCGGCAGCTGGCGGGAGCCATGGCGTACCTGGGGGCCCGCGGGCTGGTGCACCGAGACCTCGCTACGCGCAACCTACTGCTGGCGTCGCCGCGCACCATCAAGGTGGCTGACTTCGGGCTGGTGCGGCCTCTGGGCGGTGCCCGGGGCCGCTACGTCATGGGCGGGCCCCGCCCTATCCCCTACGCCTGGTGTGCCCCAGAGAGCCTGCGCCACGGAGCCTTCTCGTCTGCCTCGGACGTGTGGATGTTTGGGGTGACGCTGTGGGAGATGTTCTCCGGGGGCGAGGAACCCTGGGCCGGGGTCCCACCGTACCTCATCCTGCAGCGGCTGGAGGACAGAGCCCGGCTGCCTAGGCCTCCCCTCTGCTCCAGGGCCCTCTACTCCCTCGCCTTGCGCTGCTGGGCCCCCCACCCTGCCGACCGGCCTAGCTTTTCCCACCTGGAGGGGCTGCTGCAAGAGGCCGGGCCTTCGGAAGCATGTTGTGTGAGGGATGTCACAGAACCAGGCGCCCTGAGGATGGAGACTGGTGACCCCATCACAGTCATCGAGGGCAGCTCCTCTTTCCACAGCCCCGACTCCACAATCTGGAAGGGCCAGAATGGTCGCACCTTCAAAGTGGGCAGCTTCCCAGCCTCGGCAGTGACGCTGGCAGATGCGGGGGGCTTGCCAGCCACCCGTCCAGTCCACAGAGGCACCCCTGCCCGGGGAGATCAACACCCAGGAAGCATAGATGGAGACAGAAAGAAGGCAAATCTTTGGGATGCGCCCCCAGCACGGGGCCAGAGGAGGAACATGCCCCTGGAGAGGATGAAAGGCATTTCCAGGAGTCTGGAGTCAGTTCTGTCCCTCGGTCCTCGTCCCACAGGGGGTGGTTCAAGCCCCCCTGAAATTCGACAAGCCAGAGCTGTGCCCCAGGGACCTCCAGGCCTGCCTCCACGCCCACCTTTATCCTCTAGCTCTCCTCAGCCCAGCCAGCCCTCTAGGGAGAGGCTTCCCTGGCCCAAAAGAAAACCCCCACACAATCACCCCATGGGAATGCCTGGAGCCCGTAAAGCCGCTGCCCTCTCTGGAGGCCTCTTGTCCGATCCTGAGTTGCAGAGGAAGATTATGGAGGTGGAGCTGAGTGTGCATGGGGTCACCCACCAGGAGTGCCAGACAGCACTAGGAGCCACTGGGGGAGATGTGGTTTCTGCCATCCGGAACCTCAAGGTAGATCAGCTCTTCCACCTGAGTAGCCGGTCCAGAGCTGACTGCTGGCGCATCCTGGAGCATTACCAGTGGGACCTCTCAGCTGCCAGCCGCTATGTCCTGGCCAGGCCCTGA

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP0190-Ab Anti-TNK1 monoclonal antibody
    Target Antigen GM-Tg-g-IP0190-Ag TNK1 protein
    ORF Viral Vector pGMLP004347 Human TNK1 Lentivirus plasmid
    ORF Viral Vector pGMLP005347 Human TNK1 Lentivirus plasmid
    ORF Viral Vector vGMLP004347 Human TNK1 Lentivirus particle
    ORF Viral Vector vGMLP005347 Human TNK1 Lentivirus particle


    Target information

    Target ID GM-IP0190
    Target Name TNK1
    Gene ID 8711, 83813, 715180, 303247, 101096181, 489470, 510356, 100061776
    Gene Symbol and Synonyms Ack-like,KOS1,TNK1,Tnk1a,Tnk1b
    Uniprot Accession Q13470
    Uniprot Entry Name TNK1_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000174292
    Target Classification Kinase

    The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]



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