Anti-™PRSS15 monoclonal antibody

Pre-made anti-™PRSS15 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to ™PRSS15/™PRSS15 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0123-Ab-1/ GM-Tg-hg-IP0123-Ab-2Anti-Human ™PRSS15 monoclonal antibodyHuman
GM-Tg-rg-IP0123-Ab-1/ GM-Tg-rg-IP0123-Ab-2Anti-Rat ™PRSS15 monoclonal antibodyRat
GM-Tg-mg-IP0123-Ab-1/ GM-Tg-mg-IP0123-Ab-2Anti-Mouse ™PRSS15 monoclonal antibodyMouse
GM-Tg-cynog-IP0123-Ab-1/ GM-Tg-cynog-IP0123-Ab-2Anti-Cynomolgus/ Rhesus macaque ™PRSS15 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0123-Ab-1/ GM-Tg-felg-IP0123-Ab-2Anti-Feline ™PRSS15 monoclonal antibodyFeline
GM-Tg-cang-IP0123-Ab-1/ GM-Tg-cang-IP0123-Ab-2Anti-Canine ™PRSS15 monoclonal antibodyCanine
GM-Tg-bovg-IP0123-Ab-1/ GM-Tg-bovg-IP0123-Ab-2Anti-Bovine ™PRSS15 monoclonal antibodyBovine
GM-Tg-equg-IP0123-Ab-1/ GM-Tg-equg-IP0123-Ab-2Anti-Equine ™PRSS15 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0123-Ab-1/ GM-Tg-hg-IP0123-Ab-2; GM-Tg-rg-IP0123-Ab-1/ GM-Tg-rg-IP0123-Ab-2;
GM-Tg-mg-IP0123-Ab-1/ GM-Tg-mg-IP0123-Ab-2; GM-Tg-cynog-IP0123-Ab-1/ GM-Tg-cynog-IP0123-Ab-2;
GM-Tg-felg-IP0123-Ab-1/ GM-Tg-felg-IP0123-Ab-2; GM-Tg-cang-IP0123-Ab-1/ GM-Tg-cang-IP0123-Ab-2;
GM-Tg-bovg-IP0123-Ab-1/ GM-Tg-bovg-IP0123-Ab-2; GM-Tg-equg-IP0123-Ab-1/ GM-Tg-equg-IP0123-Ab-2
Products NameAnti-™PRSS15 monoclonal antibody
Formatmab
Target Name™PRSS15
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-™PRSS15 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0123-Ag-1Recombinant multi-species ENTK/ ™PRSS15/ PRSS7 protein


    Target information

    Target IDGM-IP0123
    Target Name™PRSS15
    Gene ID5651,19146,288291,100423099,487700,101088868,282009,100067591
    Gene Symbol and SynonymsENTK,PRSS7,™PRSS15
    Uniprot AccessionP98073,P98072
    Uniprot Entry NameENTK_HUMAN,ENTK_BOVIN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000154646
    Target ClassificationN/A

    The target: ™PRSS15, gene name: ™PRSS15, also named as ENTK, PRSS7. This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.