Human NQO1/DHQU/ DIA4 ORF/cDNA clone-Lentivirus particle (NM_000903)
Pre-made Human NQO1/DHQU/ DIA4 Lentiviral expression plasmid for NQO1 lentivirus packaging, NQO1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
The GM Vector Core (GMVC) specializes in custom lentivirus development and offers a range of lentivirus manufacturing solutions, leveraging state-of-the-art processes. Learn more about our services.
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Product information
Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
---|---|---|---|
vGMLV000811 | Human NQO1 Lentivirus particle | Pilot Grade | 1.0E+8TU |
5.0E+8TU | |||
1.0E+9TU | |||
Research Grade | 1.0E+8TU | ||
5.0E+8TU | |||
1.0E+9TU | |||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMLV000811 |
Gene Name | NQO1 |
Accession Number | NM_000903 |
Gene ID | 1728 |
Species | Human |
Product Type | Lentivirus particle (overexpression) |
Insert Length | 825 bp |
Gene Alias | DHQU, DIA4, DTD, NMOR1, NMORI, QR1 |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Blasticidin (BSD) |
Fusion Tag | Null |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T52389-Ab | Anti-NQO1 monoclonal antibody |
Target Antigen | GM-Tg-g-T52389-Ag | NQO1 protein |
ORF Viral Vector | pGMLV000811 | Human NQO1 Lentivirus plasmid |
ORF Viral Vector | pGMLP000898 | Human NQO1 Lentivirus plasmid |
ORF Viral Vector | vGMLV000811 | Human NQO1 Lentivirus particle |
ORF Viral Vector | vGMLP000898 | Human NQO1 Lentivirus particle |
Target information
Target ID | GM-T52389 |
Target Name | NQO1 |
Gene ID | 1728, 18104, 705635, 24314, 101097859, 610935, 519632, 100067237 |
Gene Symbol and Synonyms | DHQU,DIA4,DTD,Nmo-1,Nmo1,NMOR1,NMORI,NQO1,Ox-1,Ox1,QR1 |
Uniprot Accession | P15559 |
Uniprot Entry Name | NQO1_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Cancer |
Gene Ensembl | ENSG00000181019 |
Target Classification | Tumor-associated antigen (TAA) |
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.