Human GREM2/CKTSF1B2/DAND3 ORF/cDNA clone-Lentivirus particle (NM_022469)

Cat. No.: vGMLP003417

Pre-made Human GREM2/CKTSF1B2/DAND3 Lentiviral expression plasmid for GREM2 lentivirus packaging, GREM2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLP003417 Human GREM2 Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLP003417
Gene Name GREM2
Accession Number NM_022469
Gene ID 64388
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 507 bp
Gene Alias CKTSF1B2,DAND3,PRDC,STHAG9
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTTCTGGAAGCTTTCCCTGTCCTTGTTCCTGGTGGCGGTGCTGGTGAAGGTGGCGGAAGCCCGGAAGAACCGGCCGGCGGGCGCCATCCCCTCGCCTTACAAGGACGGCAGCAGCAACAACTCGGAGAGATGGCAGCACCAGATCAAGGAGGTGCTGGCCTCCAGCCAGGAGGCCCTGGTGGTCACCGAGCGCAAGTACCTCAAGAGTGACTGGTGCAAGACGCAGCCGCTGCGGCAGACGGTGAGCGAGGAGGGCTGCCGGAGCCGCACCATCCTCAACCGCTTCTGCTACGGCCAGTGCAACTCCTTCTACATCCCGCGGCACGTGAAGAAGGAGGAGGAGTCCTTCCAGTCCTGCGCCTTCTGCAAGCCCCAGCGCGTCACCTCCGTCCTCGTGGAGCTCGAGTGCCCCGGCCTGGACCCACCCTTCCGACTCAAGAAAATCCAGAAGGTGAAGCAGTGCCGGTGCATGTCCGTGAACCTGAGCGACTCGGACAAGCAGTGA
ORF Protein Sequence MFWKLSLSLFLVAVLVKVAEARKNRPAGAIPSPYKDGSSNNSERWQHQIKEVLASSQEALVVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCYGQCNSFYIPRHVKKEEESFQSCAFCKPQRVTSVLVELECPGLDPPFRLKKIQKVKQCRCMSVNLSDSDKQ

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-SE0959-Ab Anti-GREM2/ CKTSF1B2/ DAND3 functional antibody
    Target Antigen GM-Tg-g-SE0959-Ag GREM2 protein
    ORF Viral Vector pGMLP003417 Human GREM2 Lentivirus plasmid
    ORF Viral Vector vGMLP003417 Human GREM2 Lentivirus particle


    Target information

    Target ID GM-SE0959
    Target Name GREM2
    Gene ID 64388, 23893, 708280, 289264, 101096531, 490367, 100060243
    Gene Symbol and Synonyms CKTSF1B2,DAND3,GREM2,Gremlin2,PRDC,RGD1560008,STHAG9
    Uniprot Accession Q9H772
    Uniprot Entry Name GREM2_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000180875
    Target Classification Not Available

    This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008]



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