Human CTNNB1/armadillo/CTNNB ORF/cDNA clone-Adenovirus particle (NM_001904.4)
Cat. No.: vGMAD001634
Pre-made Human CTNNB1/armadillo/CTNNB Adenovirus for CTNNB1 overexpression in-vitro and in-vivo. The CTNNB1 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified CTNNB1-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.
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Product information
Catalog No. | Product Name | Adenovirus Grade | Adenovirus quantity |
vGMAD001634 | Human CTNNB1 Adenovirus particle | Research Grade-In vitro | 1E+10PFU (1E+10pfu/ml×1ml) |
5E+10PFU (1E+10pfu/ml×5ml) | |||
1E+11PFU (1E+10pfu/ml×10ml) | |||
Research Grade-In vivo | 1E+11PFU (1E+11pfu/ml×1ml) | ||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMAD001634 |
Gene Name | CTNNB1 |
Accession Number | NM_001904.4 |
Gene ID | 1499 |
Species | Human |
Product Type | Adenovirus particle (overexpression) |
Insert Length | 2346 bp |
Gene Alias | armadillo,CTNNB,EVR7,MRD19,NEDSDV |
Fluorescent Reporter | EGFP |
Mammalian Cell Selection | Null |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | EF1 |
Resistance | Kanamycin |
Reference
Data / case study
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Associated products
Target information
Target ID | GM-T82795 |
Target Name | CTNNB1 |
Gene ID | 1499, 12387, 574265, 84353, 101097342, 477032, 539003, 100055241 |
Gene Symbol and Synonyms | armadillo,Bfc,Catnb,CTNNB,CTNNB1,EVR7,Jup,Mesc,MRD19,NEDSDV |
Uniprot Accession | P35222 |
Uniprot Entry Name | CTNB1_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, Immuno-oncology Target |
Disease | breast cancer |
Gene Ensembl | ENSG00000168036 |
Target Classification | Checkpoint-Immuno Oncology, Pathway |
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.