Human ITCH/ADMFD/AIF4 ORF/cDNA clone-Adenovirus particle (NM_001257137.3)

Cat. No.: vGMAD001304

Pre-made Human ITCH/ADMFD/AIF4 Adenovirus for ITCH overexpression in-vitro and in-vivo. The ITCH adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified ITCH-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.

Target products collection

Go to ITCH/ADMFD products collection>>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdf MSDS
pdf Datasheet

Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAD001304 Human ITCH Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAD001304
Gene Name ITCH
Accession Number NM_001257137.3
Gene ID 83737
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length 2712 bp
Gene Alias ADMFD,AIF4,AIP4,NAPP1
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Kanamycin

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T81240-Ab Anti-ITCH monoclonal antibody
    Target Antigen GM-Tg-g-T81240-Ag ITCH protein
    ORF Viral Vector pGMLV000051 Human ITCH Lentivirus plasmid
    ORF Viral Vector pGMAD001304 Human ITCH Adenovirus plasmid
    ORF Viral Vector pGMPC001096 Human ITCH Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000051 Human ITCH Lentivirus particle
    ORF Viral Vector vGMAD001304 Human ITCH Adenovirus particle


    Target information

    Target ID GM-T81240
    Target Name ITCH
    Gene ID 83737, 16396, 707640, 311567, 101086133, 477199, 508431, 100069340
    Gene Symbol and Synonyms 6720481N21Rik,8030492O04Rik,A130065M08,ADMFD,AIF4,AIP4,C230047C07Rik,ITCH,NAPP1
    Uniprot Accession Q96J02
    Uniprot Entry Name ITCH_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000078747
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.