Human DNMT3A/DNMT3A2/M.HsaIIIA ORF/cDNA clone-Adenovirus particle (NM_022552.4)

SKU: vGMAD000315
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human DNMT3A/DNMT3A2/M.HsaIIIA Adenovirus for DNMT3A overexpression in-vitro and in-vivo. The DNMT3A adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified DNMT3A-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.

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Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAD000315 Human DNMT3A Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAD000315
Gene Name DNMT3A
Accession Number NM_022552.4
Gene ID 1788
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length 2739 bp
Gene Alias DNMT3A2,M.HsaIIIA,TBRS
Fluorescent Reporter Null
Mammalian Cell Selection Null
Fusion Tag Null
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T29355-Ab Anti-DNMT3A monoclonal antibody
    Target Antigen GM-Tg-g-T29355-Ag DNMT3A protein
    ORF Viral Vector pGMLV000064 Human DNMT3A Lentivirus plasmid
    ORF Viral Vector pGMAD000315 Human DNMT3A Adenovirus plasmid
    ORF Viral Vector pGMPC000350 Human DNMT3A Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000064 Human DNMT3A Lentivirus particle
    ORF Viral Vector vGMAD000315 Human DNMT3A Adenovirus particle


    Target information

    Target ID GM-T29355
    Target Name DNMT3A
    Gene ID 1788, 13435, 694822, 444984, 100510798, 482996, 359716, 100055881
    Gene Symbol and Synonyms DNMT3A,DNMT3A2,HESJAS,M.HsaIIIA,MmuIIIA,TBRS
    Uniprot Accession Q9Y6K1
    Uniprot Entry Name DNM3A_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000119772
    Target Classification Tumor-associated antigen (TAA)

    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.