Human DNMT3A/DNMT3A2/HESJAS ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_022552.5)

SKU: pGMPC000350
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human DNMT3A/DNMT3A2/HESJAS Non-Viral expression plasmid (overexpression vector) for mouse DNMT3A overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000350
Gene Name DNMT3A
Accession Number NM_022552.5
Gene ID 1788
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 2739 bp
Gene Alias DNMT3A2,HESJAS,M.HsaIIIA,TBRS
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Amplicin

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T29355-Ab Anti-DNMT3A monoclonal antibody
    Target Antigen GM-Tg-g-T29355-Ag DNMT3A protein
    ORF Viral Vector pGMLV000064 Human DNMT3A Lentivirus plasmid
    ORF Viral Vector pGMAD000315 Human DNMT3A Adenovirus plasmid
    ORF Viral Vector pGMPC000350 Human DNMT3A Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000064 Human DNMT3A Lentivirus particle
    ORF Viral Vector vGMAD000315 Human DNMT3A Adenovirus particle


    Target information

    Target ID GM-T29355
    Target Name DNMT3A
    Gene ID 1788, 13435, 694822, 444984, 100510798, 482996, 359716, 100055881
    Gene Symbol and Synonyms DNMT3A,DNMT3A2,HESJAS,M.HsaIIIA,MmuIIIA,TBRS
    Uniprot Accession Q9Y6K1
    Uniprot Entry Name DNM3A_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000119772
    Target Classification Tumor-associated antigen (TAA)

    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]



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