Human GSK3B ORF/cDNA clone-Adeno-associate virus(AAV) particle (NM_001146156)

Cat. No.: vGMAAV001480

Pre-made Human GSK3B/ Adeno-associated virus particle for GSK3B in-vivo study, mechanism of action (MOA) research and GSK3B-associated gene therapy development.

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Target products collection

Go to GSK-3B/GSK3B/ products collection>>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name AAV serotype AAV Grade AAV quantity
vGMAAV001480 Human GSK3B Adeno-associate virus(AAV) particle AAV1, AAV2, AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2 variant(AAV2.7m8), AAV5, AAV6, AAV8, AAV8-1m, AAV8-2m, AAV8 variant (Y733F, Y447F, Y275), AAV9, AAV-Rh.10, AAV-DJ, AAV-DJ/8, AAV-Retro (Retrograde), AAV9-PHP.B, AAV9-PHP.eB, AAV9-PHP.S, AAV-BR1, AAV-2i8, AAV-SIG, AAV-VEC, AAV4, AAV6.2, AAV6.2FF Pilot Grade 1.0E+12VG/ml
5.0E+12VG/ml
1E+13VG/ml
5E+13VG/ml
1E+14VG/ml
Research Grade 1.0E+12VG/ml
5.0E+12VG/ml
1E+13VG/ml
5E+13VG/ml
1E+14VG/ml
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAAV001480
Gene Name GSK3B
Accession Number NM_001146156
Gene ID 2932
Species Human
Product Type Adeno-associate virus(AAV) particle (overexpression)
Insert Length 1263 bp
Gene Alias
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTCAGGGCGGCCCAGAACCACCTCCTTTGCGGAGAGCTGCAAGCCGGTGCAGCAGCCTTCAGCTTTTGGCAGCATGAAAGTTAGCAGAGACAAGGACGGCAGCAAGGTGACAACAGTGGTGGCAACTCCTGGGCAGGGTCCAGACAGGCCACAAGAAGTCAGCTATACAGACACTAAAGTGATTGGAAATGGATCATTTGGTGTGGTATATCAAGCCAAACTTTGTGATTCAGGAGAACTGGTCGCCATCAAGAAAGTATTGCAGGACAAGAGATTTAAGAATCGAGAGCTCCAGATCATGAGAAAGCTAGATCACTGTAACATAGTCCGATTGCGTTATTTCTTCTACTCCAGTGGTGAGAAGAAAGATGAGGTCTATCTTAATCTGGTGCTGGACTATGTTCCGGAAACAGTATACAGAGTTGCCAGACACTATAGTCGAGCCAAACAGACGCTCCCTGTGATTTATGTCAAGTTGTATATGTATCAGCTGTTCCGAAGTTTAGCCTATATCCATTCCTTTGGAATCTGCCATCGGGATATTAAACCGCAGAACCTCTTGTTGGATCCTGATACTGCTGTATTAAAACTCTGTGACTTTGGAAGTGCAAAGCAGCTGGTCCGAGGAGAACCCAATGTTTCGTATATCTGTTCTCGGTACTATAGGGCACCAGAGTTGATCTTTGGAGCCACTGATTATACCTCTAGTATAGATGTATGGTCTGCTGGCTGTGTGTTGGCTGAGCTGTTACTAGGACAACCAATATTTCCAGGGGATAGTGGTGTGGATCAGTTGGTAGAAATAATCAAGGTCCTGGGAACTCCAACAAGGGAGCAAATCAGAGAAATGAACCCAAACTACACAGAATTTAAATTCCCTCAAATTAAGGCACATCCTTGGACTAAGGTCTTCCGACCCCGAACTCCACCGGAGGCAATTGCACTGTGTAGCCGTCTGCTGGAGTATACACCAACTGCCCGACTAACACCACTGGAAGCTTGTGCACATTCATTTTTTGATGAATTACGGGACCCAAATGTCAAACTACCAAATGGGCGAGACACACCTGCACTCTTCAACTTCACCACTCAAGAACTGTCAAGTAATCCACCTCTGGCTACCATCCTTATTCCTCCTCATGCTCGGATTCAAGCAGCTGCTTCAACCCCCACAAATGCCACAGCAGCGTCAGATGCTAATACTGGAGACCGTGGACAGACCAATAATGCTGCTTCTGCATCAGCTTCCAACTCCACCTGA
ORF Protein Sequence MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANTGDRGQTNNAASASASNST

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T70977-Ab Anti-GSK-3B monoclonal antibody
    Target Antigen GM-Tg-g-T70977-Ag GSK-3B/GSK3B protein
    ORF Viral Vector pGMLP005802 Human GSK3B Lentivirus plasmid
    ORF Viral Vector pGMAD001170 Human GSK3B Adenovirus plasmid
    ORF Viral Vector pGMAAV000150 Human GSK3B Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAAV001480 Human GSK3B Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMLP-SPh-089 Human GSK3B Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-134 Human GSK3B Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-229 Human GSK3B Adenovirus plasmid
    ORF Viral Vector pGMAP-SPh-274 Human GSK3B Adenovirus plasmid
    ORF Viral Vector pGMPC000126 Human GSK3B Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000726 Human GSK3B Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP005802 Human GSK3B Lentivirus particle
    ORF Viral Vector vGMAD001170 Human GSK3B Adenovirus particle
    ORF Viral Vector vGMAAV000150 Human GSK3B Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAAV001480 Human GSK3B Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMLP-SPh-089 Human GSK3B Lentivirus particle
    ORF Viral Vector vGMLP-SPh-134 Human GSK3B Lentivirus particle
    ORF Viral Vector vGMAP-SPh-229 Human GSK3B Adenovirus particle
    ORF Viral Vector vGMAP-SPh-274 Human GSK3B Adenovirus particle


    Target information

    Target ID GM-T70977
    Target Name GSK-3B
    Gene ID 2932, 56637, 713114, 84027, 101081660, 478575, 790875, 100061033
    Gene Symbol and Synonyms 7330414F15Rik,8430431H08Rik,GSK-3,GSK-3beta,GSK3,GSK3B,GSK3beta
    Uniprot Accession P49841
    Uniprot Entry Name GSK3B_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000082701
    Target Classification Kinase

    The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.