Human CXCR4/CD184/D2S201E ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_003467.3)

Cat. No.: pGMPC001085
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human CXCR4/CD184/D2S201E Non-Viral expression plasmid (overexpression vector) for mouse CXCR4 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC001085
Gene Name CXCR4
Accession Number NM_003467.3
Gene ID 7852
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1059 bp
Gene Alias CD184,D2S201E,FB22,HM89,HSY3RR,LAP-3,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM,WHIMS,WHIMS1
Fluorescent Reporter Null
Mammalian Cell Selection Null
Fusion Tag MYC (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-600 Pre-Made Ulocuplumab biosimilar, Whole mAb, Anti-CXCR4 Antibody: Anti-FB22/HM89/LAP3/LCR1/NPYR/WHIM/CD184/LAP-3/LESTR/NPY3R/NPYRL/WHIMS/HSY3RR/NPYY3R/WHIMS1/D2S201E therapeutic antibody
    Target Antibody GM-Tg-g-T96079-Ab Anti-CXCR4/ CD184/ D2S201E monoclonal antibody
    Target Antigen GM-Tg-g-T96079-Ag CXCR4 VLP (virus-like particle)
    Cytokine cks-Tg-g-GM-T96079 chemokine (C-X-C motif) receptor 4 (CXCR4) protein & antibody
    ORF Viral Vector pGMLP000599 Human CXCR4 Lentivirus plasmid
    ORF Viral Vector pGMLP003262 Human CXCR4 Lentivirus plasmid
    ORF Viral Vector pGMLV000634 Human CXCR4 Lentivirus plasmid
    ORF Viral Vector pGMLV000695 Human CXCR4 Lentivirus plasmid
    ORF Viral Vector pGMLV001389 Human CXCR4 Lentivirus plasmid
    ORF Viral Vector pGMPC000631 Human CXCR4 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001085 Human CXCR4 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP000599 Human CXCR4 Lentivirus particle
    ORF Viral Vector vGMLP003262 Human CXCR4 Lentivirus particle
    ORF Viral Vector vGMLV000634 Human CXCR4 Lentivirus particle
    ORF Viral Vector vGMLV000695 Human CXCR4 Lentivirus particle
    ORF Viral Vector vGMLV001389 Human CXCR4 Lentivirus particle


    Target information

    Target ID GM-T96079
    Target Name CXCR4
    Gene ID 7852, 12767, 707329, 60628, 493676, 119863891, 281736, 100050974
    Gene Symbol and Synonyms b2b220Clo,CD184,Cmkar4,CXC-R4,CXCR-4,CXCR4,D2S201E,FB22,HM89,HSY3RR,LAP-3,LAP3,LCR1,LESTR,LOC119863891,NPY3R,NPYR,NPYRL,NPYY3R,PB-CKR,PBSF/SDF-1,Sdf1r,WHIM,WHIMS,WHIMS1
    Uniprot Accession P61073
    Uniprot Entry Name CXCR4_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
    Disease Cancer
    Gene Ensembl ENSG00000121966
    Target Classification Checkpoint-Immuno Oncology, GPCR, Tumor-associated antigen (TAA)

    This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]



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