Human DRD2/D2DR/D2R ORF/cDNA clone-Lentivirus plasmid (NM_000795.3)

Cat. No.: pGMLV000466
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human DRD2/D2DR/D2R Lentiviral expression plasmid for DRD2 lentivirus packaging, DRD2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLV000466
Gene Name DRD2
Accession Number NM_000795.3
Gene ID 1813
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1332 bp
Gene Alias D2DR,D2R
Fluorescent Reporter ZsGreen-Firefly luciferase
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T67162-Ab Anti-DRD2/ D2R/ D2DR monoclonal antibody
    Target Antigen GM-Tg-g-T67162-Ag D2R/DRD2 VLP (virus-like particle)
    ORF Viral Vector pGMLV000444 Human DRD2 Lentivirus plasmid
    ORF Viral Vector pGMLV000466 Human DRD2 Lentivirus plasmid
    ORF Viral Vector pGMLV000806 Human DRD2 Lentivirus plasmid
    ORF Viral Vector pGMAP000308 Human DRD2 Adenovirus plasmid
    ORF Viral Vector pGMPC001516 Human DRD2 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000444 Human DRD2 Lentivirus particle
    ORF Viral Vector vGMLV000466 Human DRD2 Lentivirus particle
    ORF Viral Vector vGMLV000806 Human DRD2 Lentivirus particle
    ORF Viral Vector vGMAP000308 Human DRD2 Adenovirus particle


    Target information

    Target ID GM-T67162
    Target Name D2R
    Gene ID 1813, 13489, 694181, 24318, 101096838, 403701, 281126, 100062195
    Gene Symbol and Synonyms D2DR,D2R,Drd-2,DRD2
    Uniprot Accession P14416
    Uniprot Entry Name DRD2_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000149295
    Target Classification GPCR, Tumor-associated antigen (TAA)

    This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]



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