Human SPARC/BM-40/OI17 ORF/cDNA clone-Lentivirus plasmid (NM_003118.3)

Cat. No.: pGMLV000261
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human SPARC/BM-40/OI17 Lentiviral expression plasmid for SPARC lentivirus packaging, SPARC lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV000261
Gene Name SPARC
Accession Number NM_003118.3
Gene ID 6678
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 912 bp
Gene Alias BM-40,OI17,ON
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T09439-Ab Anti-SPRC/ SPARC/ BM-40 monoclonal antibody
    Target Antigen GM-Tg-g-T09439-Ag SPARC VLP (virus-like particle)
    ORF Viral Vector pGMLV000261 Human SPARC Lentivirus plasmid
    ORF Viral Vector pGMAP000365 Human SPARC Adenovirus plasmid
    ORF Viral Vector vGMLV000261 Human SPARC Lentivirus particle
    ORF Viral Vector vGMAP000365 Human SPARC Adenovirus particle


    Target information

    Target ID GM-T09439
    Target Name SPARC
    Gene ID 6678, 20692, 712388, 24791, 101099861, 100855736, 282077, 100060119
    Gene Symbol and Synonyms BM-40,OI17,ON,ONT,SPARC
    Uniprot Accession P09486
    Uniprot Entry Name SPRC_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000113140
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2015]



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