Human AGTR1/AG2S/AGTR1B ORF/cDNA clone-Lentivirus plasmid (NM_009585)

SKU: pGMLV000160
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human AGTR1/AG2S/AGTR1B Lentiviral expression plasmid for AGTR1 lentivirus packaging, AGTR1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLV000160
Gene Name AGTR1
Accession Number NM_009585
Gene ID 185
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1080 bp
Gene Alias AG2S,AGTR1B,AT1,AT1AR,AT1B,AT1BR,AT1R,AT2R1,HAT1R
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
Sequence 正确

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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T74456-Ab Anti-AGTR1/ AG2SB/ AT1 monoclonal antibody
    Target Antigen GM-Tg-g-T74456-Ag AGTR1 VLP (virus-like particle)
    ORF Viral Vector pGMLV000160 Human AGTR1 Lentivirus plasmid
    ORF Viral Vector pGMAD000019 Human AGTR1 Adenovirus plasmid
    ORF Viral Vector pGMPC000236 Human AGTR1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000160 Human AGTR1 Lentivirus particle
    ORF Viral Vector vGMAD000019 Human AGTR1 Adenovirus particle


    Target information

    Target ID GM-T74456
    Target Name AGTR1
    Gene ID 185, 11608, 712773, 81638, 101082936, 403836, 281607, 100059005
    Gene Symbol and Synonyms AG2S,Agtr-1b,AGTR1,AGTR1B,Angtr-1b,AT1,AT1AR,AT1B,AT1BR,AT1R,AT2R1,AT2R1B,AT3,AT1R,ATR1,HAT1R
    Uniprot Accession P30556
    Uniprot Entry Name AGTR1_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000144891
    Target Classification GPCR

    Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2020]



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