Human AGTR1/AG2S/AGTR1B ORF/cDNA clone-Adenovirus plasmid (NM_000685.4)

SKU: pGMAD000019
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human AGTR1/AG2S/AGTR1B adenoviral expression plasmid for AGTR1 adenovirus packaging, AGTR1 adenovirus.

Our GM-Adenovirus vector is optimized with the GMVC-modified Adeasy adenovirus packaging system. Find more about the GMVC-modified adenovirus packaging system.

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Product Description

Catalog ID pGMAD000019
Gene Name AGTR1
Accession Number NM_000685.4
Gene ID 185
Species Human
Product Type Adenovirus plasmid (overexpression)
Insert Length 1080 bp
Gene Alias AG2S,AGTR1B,AT1,AT1AR,AT1B,AT1BR,AT1R,AT2R1,HAT1R
Fluorescent Reporter GFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T74456-Ab Anti-AGTR1/ AG2SB/ AT1 monoclonal antibody
    Target Antigen GM-Tg-g-T74456-Ag AGTR1 VLP (virus-like particle)
    ORF Viral Vector pGMLV000160 Human AGTR1 Lentivirus plasmid
    ORF Viral Vector pGMAD000019 Human AGTR1 Adenovirus plasmid
    ORF Viral Vector pGMPC000236 Human AGTR1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000160 Human AGTR1 Lentivirus particle
    ORF Viral Vector vGMAD000019 Human AGTR1 Adenovirus particle


    Target information

    Target ID GM-T74456
    Target Name AGTR1
    Gene ID 185, 11608, 712773, 81638, 101082936, 403836, 281607, 100059005
    Gene Symbol and Synonyms AG2S,Agtr-1b,AGTR1,AGTR1B,Angtr-1b,AT1,AT1AR,AT1B,AT1BR,AT1R,AT2R1,AT2R1B,AT3,AT1R,ATR1,HAT1R
    Uniprot Accession P30556
    Uniprot Entry Name AGTR1_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000144891
    Target Classification GPCR

    Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2020]



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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.