Human IL31/IL-31 ORF/cDNA clone-Lentivirus plasmid (NM_001014336)

Cat. No.: pGMLP004789
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human IL31/IL-31 Lentiviral expression plasmid for IL31 lentivirus packaging, IL31 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP004789
Gene Name IL31
Accession Number NM_001014336
Gene ID 386653
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 495 bp
Gene Alias IL-31
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCCTCTCACTCAGGCCCCTCGACGTCTGTGCTCTTTCTGTTCTGCTGCCTGGGAGGCTGGCTGGCCTCCCACACGTTGCCCGTCCGTTTACTACGACCAAGTGATGATGTACAGAAAATAGTCGAGGAATTACAGTCCCTCTCGAAGATGCTTTTGAAAGATGTGGAGGAAGAGAAGGGCGTGCTCGTGTCCCAGAATTACACGCTGCCGTGTCTCAGCCCTGACGCCCAGCCGCCAAACAACATCCACAGCCCAGCCATCCGGGCATATCTCAAGACAATCAGACAGCTAGACAACAAATCTGTTATTGATGAGATCATAGAGCACCTCGACAAACTCATATTTCAAGATGCACCAGAAACAAACATTTCTGTGCCAACAGACACCCATGAATGTAAACGCTTCATCCTGACTATTTCTCAACAGTTTTCAGAGTGCATGGACCTCGCACTAAAATCATTGACCTCTGGAGCCCAACAGGCCACCACTTAA
ORF Protein Sequence MASHSGPSTSVLFLFCCLGGWLASHTLPVRLLRPSDDVQKIVEELQSLSKMLLKDVEEEKGVLVSQNYTLPCLSPDAQPPNNIHSPAIRAYLKTIRQLDNKSVIDEIIEHLDKLIFQDAPETNISVPTDTHECKRFILTISQQFSECMDLALKSLTSGAQQATT

Reference




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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-319 Pre-Made Lokivetmab biosimilar, Canine Whole Mab: Anti-IL31 therapeutic antibody
    Biosimilar GMP-Bios-ab-155 Pre-Made Dovanvetmab biosimilar, Feline Whole Mab: Anti-IL31 (Feline) therapeutic antibody
    Target Antibody GM-Tg-g-T11701-Ab Anti-IL31/ IL-31 functional antibody
    Target Antigen GM-Tg-g-T11701-Ag IL31 protein
    Cytokine cks-Tg-g-GM-T11701 interleukin 31 (Il31) protein & antibody
    ORF Viral Vector pGMLP004789 Human IL31 Lentivirus plasmid
    ORF Viral Vector pGMLP-IL-035 Human IL31 Lentivirus plasmid
    ORF Viral Vector pGMAP-IL-118 Human IL31 Adenovirus plasmid
    ORF Viral Vector vGMLP004789 Human IL31 Lentivirus particle
    ORF Viral Vector vGMLP-IL-035 Human IL31 Lentivirus particle
    ORF Viral Vector vGMAP-IL-118 Human IL31 Adenovirus particle


    Target information

    Target ID GM-T11701
    Target Name IL31
    Gene ID 386653, 76399, 701655, 690028, 105261056, 100302725, 102149194
    Gene Symbol and Synonyms 1700013B14Rik,AABR07036324.1,IL-31,IL31
    Uniprot Accession Q6EBC2
    Uniprot Entry Name IL31_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target, INN Index, Cytokine Target
    Disease Not Available
    Gene Ensembl ENSG00000204671
    Target Classification Not Available

    IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]



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