Human BDNF/MGC34632 ORF/cDNA clone-Lentivirus plasmid (BC029795)

Cat. No.: pGMLP004025
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human BDNF/MGC34632 Lentiviral expression plasmid for BDNF lentivirus packaging, BDNF lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.


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Product Description

Catalog ID pGMLP004025
Gene Name BDNF
Accession Number BC029795
Gene ID 627
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 744 bp
Gene Alias MGC34632
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGACCATCCTTTTCCTTACTATGGTTATTTCATACTTTGGTTGCATGAAGGCTGCCCCCATGAAAGAAGCAAACATCCGAGGACAAGGTGGCTTGGCCTACCCAGGTGTGCGGACCCATGGGACTCTGGAGAGCGTGAATGGGCCCAAGGCAGGTTCAAGAGGCTTGACATCATTGGCTGACACTTTCGAACACATGATAGAAGAGCTGTTGGATGAGGACCAGAAAGTTCGGCCCAATGAAGAAAACAATAAGGACGCAGACTTGTACACGTCCAGGGTGATGCTCAGTAGTCAAGTGCCTTTGGAGCCTCCTCTTCTCTTTCTGCTGGAGGAATACAAAAATTACCTAGACGCTGCAAACATGTCCATGAGGGTCCGGCGCCACTCTGACCCTGCCCGCCGAGGGGAGCTGAGCGTGTGTGACAGTATTAGTGAGTGGGTAACGGCGGCAGACAAAAAGACTGCAGTGGACATGTCGGGCGGGACGGTCACAGTCCTTGAAAAGGTCCCTGTATCAAAAGGCCAACTGAAGCAATACTTCTACGAGACCAAGTGCAATCCCATGGGTTACACAAAAGAAGGCTGCAGGGGCATAGACAAAAGGCATTGGAACTCCCAGTGCCGAACTACCCAGTCGTACGTGCGGGCCCTTACCATGGATAGCAAAAAGAGAATTGGCTGGCGATTCATAAGGATAGACACTTCTTGTGTATGTACATTGACCATTAAAAGGGGAAGATAG
ORF Protein Sequence MTILFLTMVISYFGCMKAAPMKEANIRGQGGLAYPGVRTHGTLESVNGPKAGSRGLTSLADTFEHMIEELLDEDQKVRPNEENNKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T93122-Ab Anti-BDNF/ ANON2/ BULN2 functional antibody
    Target Antigen GM-Tg-g-T93122-Ag BDNF protein
    ORF Viral Vector pGMLP004025 Human BDNF Lentivirus plasmid
    ORF Viral Vector pGMAD000577 Human BDNF Adenovirus plasmid
    ORF Viral Vector pGMAAV000575 Human BDNF Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAP000316 Human BDNF Adenovirus plasmid
    ORF Viral Vector pGMPC000136 Human BNDF Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000188 Human BDNF Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC004727 Human BDNF Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP004025 Human BDNF Lentivirus particle
    ORF Viral Vector vGMAD000577 Human BDNF Adenovirus particle
    ORF Viral Vector vGMAAV000575 Human BDNF Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAP000316 Human BDNF Adenovirus particle


    Target information

    Target ID GM-T93122
    Target Name BDNF
    Gene ID 627, 12064, 701245, 24225, 493690, 403461, 617701, 100009689
    Gene Symbol and Synonyms ANON2,BDNF,BULN2
    Uniprot Accession P23560
    Uniprot Entry Name BDNF_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target
    Disease Prostate Cancer, ovarian cancer, Overactive bladder, Autism, mental retardation, Allergic reactions, Asthma, Parkinson's Disease
    Gene Ensembl ENSG00000176697
    Target Classification Not Available

    This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. [provided by RefSeq, Nov 2015]



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