Human BDNF/ANON2/BULN2 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_170735.5)
Cat. No.: pGMAAV000575
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human BDNF/ANON2/BULN2 Adeno-associated virus expression plasmid (ITR-vector) for BDNF AAV packaging, BDNF AAV production.The purified Human BDNF/ANON2/BULN2 AAV particle serves as an invaluable asset for in-depth in vivo BDNF studies, mechanism of action (MOA) research, and the evolution of BDNF-associated gene therapy strategies.
Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.
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Product Description
Catalog ID | pGMAAV000575 |
Gene Name | BDNF |
Accession Number | NM_170735.5 |
Gene ID | 627 |
Species | Human |
Product Type | Adeno-associate virus(AAV) plasmid (overexpression) |
Insert Length | 744 bp |
Gene Alias | ANON2,BULN2 |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Null |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
ORF Nucleotide Sequence | ATGACCATCCTTTTCCTTACTATGGTTATTTCATACTTTGGTTGCATGAAGGCTGCCCCCATGAAAGAAGCAAACATCCGAGGACAAGGTGGCTTGGCCTACCCAGGTGTGCGGACCCATGGGACTCTGGAGAGCGTGAATGGGCCCAAGGCAGGTTCAAGAGGCTTGACATCATTGGCTGACACTTTCGAACACGTGATAGAAGAGCTGTTGGATGAGGACCAGAAAGTTCGGCCCAATGAAGAAAACAATAAGGACGCAGACTTGTACACGTCCAGGGTGATGCTCAGTAGTCAAGTGCCTTTGGAGCCTCCTCTTCTCTTTCTGCTGGAGGAATACAAAAATTACCTAGATGCTGCAAACATGTCCATGAGGGTCCGGCGCCACTCTGACCCTGCCCGCCGAGGGGAGCTGAGCGTGTGTGACAGTATTAGTGAGTGGGTAACGGCGGCAGACAAAAAGACTGCAGTGGACATGTCGGGCGGGACGGTCACAGTCCTTGAAAAGGTCCCTGTATCAAAAGGCCAACTGAAGCAATACTTCTACGAGACCAAGTGCAATCCCATGGGTTACACAAAAGAAGGCTGCAGGGGCATAGACAAAAGGCATTGGAACTCCCAGTGCCGAACTACCCAGTCGTACGTGCGGGCCCTTACCATGGATAGCAAAAAGAGAATTGGCTGGCGATTCATAAGGATAGACACTTCTTGTGTATGTACATTGACCATTAAAAGGGGAAGATAG |
ORF Protein Sequence | MTILFLTMVISYFGCMKAAPMKEANIRGQGGLAYPGVRTHGTLESVNGPKAGSRGLTSLADTFEHVIEELLDEDQKVRPNEENNKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T93122-Ab | Anti-BDNF/ ANON2/ BULN2 functional antibody |
Target Antigen | GM-Tg-g-T93122-Ag | BDNF protein |
ORF Viral Vector | pGMLP004025 | Human BDNF Lentivirus plasmid |
ORF Viral Vector | pGMAD000577 | Human BDNF Adenovirus plasmid |
ORF Viral Vector | pGMAAV000575 | Human BDNF Adeno-associate virus(AAV) plasmid |
ORF Viral Vector | pGMAP000316 | Human BDNF Adenovirus plasmid |
ORF Viral Vector | pGMPC000136 | Human BNDF Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | pGMPC000188 | Human BDNF Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | pGMPC004727 | Human BDNF Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | vGMLP004025 | Human BDNF Lentivirus particle |
ORF Viral Vector | vGMAD000577 | Human BDNF Adenovirus particle |
ORF Viral Vector | vGMAAV000575 | Human BDNF Adeno-associate virus(AAV) particle |
ORF Viral Vector | vGMAP000316 | Human BDNF Adenovirus particle |
Target information
Target ID | GM-T93122 |
Target Name | BDNF |
Gene ID | 627, 12064, 701245, 24225, 493690, 403461, 617701, 100009689 |
Gene Symbol and Synonyms | ANON2,BDNF,BULN2 |
Uniprot Accession | P23560 |
Uniprot Entry Name | BDNF_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target |
Disease | Prostate Cancer, ovarian cancer, Overactive bladder, Autism, mental retardation, Allergic reactions, Asthma, Parkinson's Disease |
Gene Ensembl | ENSG00000176697 |
Target Classification | Not Available |
This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. [provided by RefSeq, Nov 2015]
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