Human MDK/ARAP/MK ORF/cDNA clone-Lentivirus plasmid (NM_002391)

Cat. No.: pGMLP000499
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human MDK/ARAP/MK Lentiviral expression plasmid for MDK lentivirus packaging, MDK lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000499
Gene Name MDK
Accession Number NM_002391
Gene ID 4192
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 432 bp
Gene Alias ARAP,MK,NEGF2
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCAGCACCGAGGCTTCCTCCTCCTCACCCTCCTCGCCCTGCTGGCGCTCACCTCCGCGGTCGCCAAAAAGAAAGATAAGGTGAAGAAGGGCGGCCCGGGGAGCGAGTGCGCTGAGTGGGCCTGGGGGCCCTGCACCCCCAGCAGCAAGGATTGCGGCGTGGGTTTCCGCGAGGGCACCTGCGGGGCCCAGACCCAGCGCATCCGGTGCAGGGTGCCCTGCAACTGGAAGAAGGAGTTTGGAGCCGACTGCAAGTACAAGTTTGAGAACTGGGGTGCGTGTGATGGGGGCACAGGCACCAAAGTCCGCCAAGGCACCCTGAAGAAGGCGCGCTACAATGCTCAGTGCCAGGAGACCATCCGCGTCACCAAGCCCTGCACCCCCAAGACCAAAGCAAAGGCCAAAGCCAAGAAAGGGAAGGGAAAGGACTAG
ORF Protein Sequence MQHRGFLLLTLLALLALTSAVAKKKDKVKKGGPGSECAEWAWGPCTPSSKDCGVGFREGTCGAQTQRIRCRVPCNWKKEFGADCKYKFENWGACDGGTGTKVRQGTLKKARYNAQCQETIRVTKPCTPKTKAKAKAKKGKGKD

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T03878-Ab Anti-MK/ Midkine/ MDK functional antibody
    Target Antigen GM-Tg-g-T03878-Ag Midkine/MDK protein
    ORF Viral Vector pGMLP000499 Human MDK Lentivirus plasmid
    ORF Viral Vector pGMAD001596 Human MDK Adenovirus plasmid
    ORF Viral Vector pGMAP000446 Human MDK Adenovirus plasmid
    ORF Viral Vector pGMAP000465 Human MDK Adenovirus plasmid
    ORF Viral Vector vGMLP000499 Human MDK Lentivirus particle
    ORF Viral Vector vGMAD001596 Human MDK Adenovirus particle
    ORF Viral Vector vGMAP000446 Human MDK Adenovirus particle
    ORF Viral Vector vGMAP000465 Human MDK Adenovirus particle


    Target information

    Target ID GM-T03878
    Target Name Midkine
    Gene ID 4192, 17242, 714591, 81517, 101087941, 119864230, 280852, 100147284
    Gene Symbol and Synonyms ARAP,MDK,Mek,MK,NEGF2
    Uniprot Accession P21741
    Uniprot Entry Name MK_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target
    Disease Lung Cancer, Malignant neoplasm of bladder, Urinary bladder urothelial carcinoma, breast cancer
    Gene Ensembl ENSG00000110492
    Target Classification Not Available

    This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]



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