Human IL27/IL-27/ IL-27A ORF/cDNA clone-Lentivirus plasmid (NM_145659)

Pre-made Human IL27/IL-27/ IL-27A Lentiviral expression plasmid for IL27 lentivirus packaging, IL27 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMLP-IL-034 Human IL27 Lentivirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMLP-IL-034
Gene Name IL27
Accession Number NM_145659
Gene ID 246778
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 732 bp
Gene Alias IL-27, IL-27A, IL27A, IL27p28, IL30, p28
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
Sequence ATGGGCCAGACGGCAGGCGACCTTGGCTGGCGGCTCAGCCTGTTGCTGCTTCCCTTGCTCCTGGTTCAAGCTGGTGTCTGGGGATTCCCAAGGCCCCCAGGGAGGCCCCAGCTGAGCCTGCAGGAGCTGCGGAGGGAGTTCACAGTCAGCCTGCATCTCGCCAGGAAGCTGCTCTCCGAGGTTCGGGGCCAGGCCCACCGCTTTGCGGAATCTCACCTGCCAGGAGTGAACCTGTACCTCCTGCCCCTGGGAGAGCAGCTCCCTGATGTTTCCCTGACCTTCCAGGCCTGGCGCCGCCTCTCTGACCCGGAGCGTCTCTGCTTCATCTCCACCACGCTTCAGCCCTTCCATGCCCTGCTGGGAGGGCTGGGGACCCAGGGCCGCTGGACCAACATGGAGAGGATGCAGCTGTGGGCCATGAGGCTGGACCTCCGCGATCTGCAGCGGCACCTCCGCTTCCAGGTGCTGGCTGCAGGATTCAACCTCCCGGAGGAGGAGGAGGAGGAAGAGGAGGAGGAGGAGGAGGAGAGGAAGGGGCTGCTCCCAGGGGCACTGGGCAGCGCCTTACAGGGCCCGGCCCAGGTGTCCTGGCCCCAGCTCCTCTCCACCTACCGCCTGCTGCACTCCTTGGAGCTCGTCTTATCTCGGGCCGTGCGGGAGTTGCTGCTGCTGTCCAAGGCTGGGCACTCAGTCTGGCCCTTGGGGTTCCCAACATTGAGCCCCCAGCCCTGA

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-SE1026-Ab Anti-IL27A/ IL27/ IL-27 functional antibody
    Target Antigen GM-Tg-g-SE1026-Ag IL27 protein
    ORF Viral Vector pGMLP002772 Human IL27 Lentivirus plasmid
    ORF Viral Vector pGMLP-IL-034 Human IL27 Lentivirus plasmid
    ORF Viral Vector pGMAP-IL-117 Human IL27 Adenovirus plasmid
    ORF Viral Vector vGMLP002772 Human IL27 Lentivirus particle
    ORF Viral Vector vGMLP-IL-034 Human IL27 Lentivirus particle
    ORF Viral Vector vGMAP-IL-117 Human IL27 Adenovirus particle


    Target information

    Target ID GM-SE1026
    Target Name IL27
    Gene ID 246778, 246779, 708678, 365368, 101093822, 607880, 614927, 100066317
    Gene Symbol and Synonyms IL-27,IL-27-A,IL-27A,IL-27alpha,IL-27p28,IL27,IL27-A,IL27A,IL27p28,IL30,p28,RGD1561420
    Uniprot Accession Q8NEV9
    Uniprot Entry Name IL27A_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Not Available
    Disease Cancer
    Gene Ensembl ENSG00000197272
    Target Classification Tumor-associated antigen (TAA)

    The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008]



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