Human IL25/IL17E ORF/cDNA clone-Lentivirus plasmid (NM_022789)

Cat. No.: pGMLP-IL-032
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human IL25/IL17E Lentiviral expression plasmid for IL25 lentivirus packaging, IL25 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP-IL-032
Gene Name IL25
Accession Number NM_022789
Gene ID 64806
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 534 bp
Gene Alias IL17E
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAGGGAGCGACCCAGATTAGGTGAGGACAGTTCTCTCATTAGCCTTTTCCTACAGGTGGTTGCATTCTTGGCAATGGTCATGGGAACCCACACCTACAGCCACTGGCCCAGCTGCTGCCCCAGCAAAGGGCAGGACACCTCTGAGGAGCTGCTGAGGTGGAGCACTGTGCCTGTGCCTCCCCTAGAGCCTGCTAGGCCCAACCGCCACCCAGAGTCCTGTAGGGCCAGTGAAGATGGACCCCTCAACAGCAGGGCCATCTCCCCCTGGAGATATGAGTTGGACAGAGACTTGAACCGGCTCCCCCAGGACCTGTACCACGCCCGTTGCCTGTGCCCGCACTGCGTCAGCCTACAGACAGGCTCCCACATGGACCCCCGGGGCAACTCGGAGCTGCTCTACCACAACCAGACTGTCTTCTACCGGCGGCCATGCCATGGCGAGAAGGGCACCCACAAGGGCTACTGCCTGGAGCGCAGGCTGTACCGTGTTTCCTTAGCTTGTGTGTGTGTGCGGCCCCGTGTGATGGGCTAG
ORF Protein Sequence MRERPRLGEDSSLISLFLQVVAFLAMVMGTHTYSHWPSCCPSKGQDTSEELLRWSTVPVPPLEPARPNRHPESCRASEDGPLNSRAISPWRYELDRDLNRLPQDLYHARCLCPHCVSLQTGSHMDPRGNSELLYHNQTVFYRRPCHGEKGTHKGYCLERRLYRVSLACVCVRPRVMG

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T62241-Ab Anti-IL25/ IL17E functional antibody
    Target Antigen GM-Tg-g-T62241-Ag IL25 protein
    Cytokine cks-Tg-g-GM-T62241 Interleukin 25 (IL25) protein & antibody
    ORF Viral Vector pGMAP000371 Human IL25 Adenovirus plasmid
    ORF Viral Vector pGMLP-IL-032 Human IL25 Lentivirus plasmid
    ORF Viral Vector pGMAP-IL-115 Human IL25 Adenovirus plasmid
    ORF Viral Vector vGMAP000371 Human IL25 Adenovirus particle
    ORF Viral Vector vGMLP-IL-032 Human IL25 Lentivirus particle
    ORF Viral Vector vGMAP-IL-115 Human IL25 Adenovirus particle


    Target information

    Target ID GM-T62241
    Target Name IL25
    Gene ID 64806, 140806, 713943, 501996, 101095746, 480252, 526816, 111768801
    Gene Symbol and Synonyms IL-17e,IL-25,IL17E,IL25,RGD1561632
    Uniprot Accession Q9H293
    Uniprot Entry Name IL25_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target, Cytokine Target
    Disease Not Available
    Gene Ensembl ENSG00000166090
    Target Classification Not Available

    The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]



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