Human BMP7/OP-1 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_001719)

SKU: pGMAAV000461
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human BMP7/OP-1 Adeno-associated virus expression plasmid (ITR-vector) for BMP7 AAV packaging, BMP7 AAV production.The purified Human BMP7/OP-1 AAV particle serves as an invaluable asset for in-depth in vivo BMP7 studies, mechanism of action (MOA) research, and the evolution of BMP7-associated gene therapy strategies.

Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.

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Product Description

Catalog ID pGMAAV000461
Gene Name BMP7
Accession Number NM_001719
Gene ID 655
Species Human
Product Type Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length 1296 bp
Gene Alias OP-1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T50289-Ab Anti-BMP7/ OP-1 functional antibody
    Target Antigen GM-Tg-g-T50289-Ag BMP7 protein
    Cytokine cks-Tg-g-GM-T50289 bone morphogenetic protein 7 (BMP7) protein & antibody
    ORF Viral Vector pGMLV000318 Human BMP7 Lentivirus plasmid
    ORF Viral Vector pGMLV000319 Human BMP7 Lentivirus plasmid
    ORF Viral Vector pGMAAV000461 Human BMP7 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAP000439 Human BMP7 Adenovirus plasmid
    ORF Viral Vector pGMLP-SPh-070 Human BMP7 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-210 Human BMP7 Adenovirus plasmid
    ORF Viral Vector vGMLV000318 Human BMP7 Lentivirus particle
    ORF Viral Vector vGMLV000319 Human BMP7 Lentivirus particle
    ORF Viral Vector vGMAAV000461 Human BMP7 Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAP000439 Human BMP7 Adenovirus particle
    ORF Viral Vector vGMLP-SPh-070 Human BMP7 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-210 Human BMP7 Adenovirus particle


    Target information

    Target ID GM-T50289
    Target Name BMP7
    Gene ID 655, 12162, 696948, 85272, 101094168, 477270, 540595, 100050299
    Gene Symbol and Synonyms BMP-7,BMP7,OP-1,OP1
    Uniprot Accession P18075
    Uniprot Entry Name BMP7_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target, Cytokine Target
    Disease Cancer
    Gene Ensembl ENSG00000101144
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients. [provided by RefSeq, Jul 2016]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.