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Human MAPT/DDPAC/ FTDP-17 ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_005910.5)
Pre-made Human MAPT/DDPAC/ FTDP-17 Adeno-associated virus expression plasmid (ITR-vector) for MAPT AAV packaging, MAPT AAV production.The purified Human MAPT/DDPAC/ FTDP-17 AAV particle serves as an invaluable asset for in-depth in vivo MAPT studies, mechanism of action (MOA) research, and the evolution of MAPT-associated gene therapy strategies.
Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.
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Product information
| Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
|---|---|---|---|
| pGMAAV000031 | Human MAPT Adeno-associate virus(AAV) plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
| GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
| High Quality (HQ) Grade | |||
| Seed | 5ug |
Product Description
| Catalog ID | pGMAAV000031 |
| Gene Name | MAPT |
| Accession Number | NM_005910.5 |
| Gene ID | 4137 |
| Species | Human |
| Product Type | Adeno-associate virus(AAV) plasmid (overexpression) |
| Insert Length | 1326 bp |
| Gene Alias | DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU |
| Fluorescent Reporter | EGFP |
| Mammalian Cell Selection | |
| Fusion Tag | Null |
| Promoter | CMV |
| Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Target information
| Target ID | GM-T45593 |
| Target Name | MAPT |
| Gene ID | 4137, 17762, 574327, 29477, 101089557, 480488, 281296, 100054638 |
| Gene Symbol and Synonyms | DDPAC,FTDP-17,MAPT,MAPTL,MAPT_0N4R,MSTD,Mtapt,MTBT1,MTBT2,PHF-tau,PPND,PPP1R103,pTau,RNPTAU,TAU,tau-40,Tau-PHF6 |
| Uniprot Accession | P10636 |
| Uniprot Entry Name | TAU_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Diagnostics Biomarker, INN Index |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000186868 |
| Target Classification | Not Available |
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.
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