Potency validation of GeneMedi's P24 antibody pairs in lentivirus-titration using sandwich ELISA

Lentiviral vectors are efficient vehicles for stable gene transfer in both dividing and non-dividing cells. This feature among others makes lentiviral vectors a powerful tool in molecular research. However, the use of lentiviruses in research studies and clinical trials requires a precise and validated titration method. Application development scientists of GDU (GeneMedi Diagnostics Unit) have developed antibody pair: anti-lentiviral p24 antigen mouse monoclonal antibody for quantitative detection of lentiviral particles titration.

Scientists of GDU have compared the lentivirus particle binding curve of our P24 antibodies (GMP-IVD-P005-Tg001-Ab01/GMP-IVD-P005-Tg001-Ab02) with other company’s. As is shown below, GeneMedi’s antibody pair has a larger linear range and better sensitivity. Besides, our antibody pair represents the best EC50.

The higher affinity, stronger stability and also the specificity of GeneMedi’s P24 antibody pair had been proved by our global CGT partners. I highly recommend our anti-lentiviral P24 mouse monoclonal antibody pair to you.

Figure 1. GeneMedi and other company's P24 antibody pairs validation with lentivirus (GMVP-LVc10) in sandwich ELISA. GeneMedi's P24 antibody pair has a larger linear range and better sensitivity, and represents the best EC50. GeneMedi’s Ab01: GMP-IVD-P005-Tg001-Ab01, GeneMedi’s Ab02: GMP-IVD-P005-Tg001-Ab02).

We show our sincere eagerness to cooperate with you. Below is the product list for our Anti-lentiviral p24 antigen mouse monoclonal antibody. If you want to order, please click the link and send email to [email protected] . Thank you!

Cat No.	Pathogen	Target	Disease	Cat No.of Antigen	Bioactivity validation of Antigen	Cat No.of Antibodies	Bioactivity validation of Antibodies	Order
GMP-IVD-P005-Tg001	immunodeficiency virus 1/2 (HIV1/2)	HIV p24 antigen	AIDS	GMP-IVD-P005-Tg001-Ag01: Recombinant immunodeficiency virus 1/2 (HIV1/2) HIV p24 antigen Protein	immunodeficiency virus 1/2 (HIV p24 antigen) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HIV p24 antigen level test of Infectious disease (AIDS) and related syndrome evaluation.	GMP-IVD-P005-Tg001-Ab01; GMP-IVD-P005-Tg001-Ab02: Anti-immunodeficiency virus 1/2 (HIV1/2) HIV p24 antigen mouse monoclonal antibody (mAb)	immunodeficiency virus 1/2 (HIV p24 antigen) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other immunodeficiency virus 1/2 (HIV p24 antigen) antibodies in HIV p24 antigen level test of Infectious disease (AIDS) and related syndrome evaluation.