Diagnostics antibodies and antigens for metabolic diseases
Metabolism is the process of making energy from the food. metabolic disease, any of the diseases or
disorders that disrupt normal metabolism, the process of converting food to energy on a cellular
level. Thousands of enzymes participating in numerous interdependent metabolic pathways carry out
this process. Metabolic diseases affect the ability of the cell to perform critical biochemical
reactions that involve the processing or transport of proteins (amino acids), carbohydrates (sugars
and starches), or lipids (fatty acids). The consequences of metabolic disorder may be severe;
intellectual disability, seizures, decreased muscle tone, organ failure, blindness, and deafness may
occur, depending on which enzyme is dysfunctional. Biomarker such as -25 hydroxyvitamin D,
procollagen type I N-terminal propeptide (PINP), β-isomerized C-terminal telopeptides, 25-hydroxy
(OH) Vitamin, S-adenosylhomocysteine (AdoHcy) hydrolase, cystathionine-β-synthase enzyme,
Phospholipase A2, Retinol binding protein 4 and so on are suitable for monitoring metabolic disease.
Detecting the quantity of these marker proteins from different samples may benefit from ELISA,
Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent
immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and
POCT.
Classification:
25-OH-(VD3+VD2)
PINP
N-MID OC
β-CTx
25-OH-VD
25-OH-VD-3
SAHH
CBL
CBS
LP-PLA2
RBP4
hGH
Biotin
EtG