Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) monoclonal antibody (mAb)

PK Research Our innovative Anti-SN-38 Monoclonal Antibody is developed for accuracy in PK studies of antibody-drug conjugates. It gives better understanding about the distribution and metabolism of SN-38 conjugated ADCs which helps the researchers to find better strategies for ADC therapy.

Check the application of 7-Ethyl-10-hydroxycamptothecin (SN-38) in ADCs


Order information


Catalog No. Product Name Size Price(In USD)
GTU-Bios-SN-38-Ab-1 Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) human monoclonal antibody (mAb) 1mg 1690
GTU-Bios-SN-38-Ab-2 Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) mouse monoclonal antibody (mAb) 1mg 1690
GTU-Bios-SN-38-Ab-3 Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) mouse monoclonal antibody (mAb) 1mg 1690

Size: 1mg | 10mg | 100mg


Description


Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) human monoclonal antibody (mAb)

Cat No. GTU-Bios-SN-38-Ab-1
Product Name Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) human monoclonal antibody (mAb)
Target 7-Ethyl-10-hydroxycamptothecin (SN-38)
Expression platform mammalian cell
Isotypes Human IgG1
Bioactivity validation 7-Ethyl-10-hydroxycamptothecin (SN-38) binding, Competitive immunoassay validation (Competitive ELISA) in 7-Ethyl-10-hydroxycamptothecin (SN-38) level test.
Tag hFc
Products description Anti-7-Ethyl-10-hydroxycamptothecin (SN-38) monoclonal antibody is expressed from mammalian cell.
Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application Competitive immunoassay validation (Competitive ELISA) and other Immunoassay, PK & PD assay for SN-38 payload of Antibody-drug Conjugate (ADC).
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) mouse monoclonal antibody (mAb)

Cat No. GTU-Bios-SN-38-Ab-2, GTU-Bios-SN-38-Ab-3
Product Name Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) mouse monoclonal antibody (mAb)
Target 7-Ethyl-10-hydroxycamptothecin (SN-38)
Expression platform mammalian cell
Isotypes Mouse IgG
Bioactivity validation 7-Ethyl-10-hydroxycamptothecin (SN-38) binding, Competitive immunoassay validation (Competitive ELISA) in 7-Ethyl-10-hydroxycamptothecin (SN-38) level test.
Tag mFc
Products description Anti-7-Ethyl-10-hydroxycamptothecin (SN-38)) mouse monoclonal antibody (mAb) is expressed from mammalian cell.
Species Mouse
Purity Purity: ≥95% (SDS-PAGE)
Application Competitive immunoassay validation (Competitive ELISA) and other Immunoassay, PK & PD assay for SN-38 payload of Antibody-drug Conjugate (ADC).
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Validation Data


    Click to get more Data / Case study about the product.



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