Anti-G4S monoclonal antibody (mAb)

The Anti-G4S monoclonal antibody (mAb) for CAR-T cell preparation implies the utilization of G4S linker-based antibody in the course of lentivirus packaging. This approach improves the avidity and selectivity of CAR-T cells - T cells that have been genetically modified to bear a chimeric antigen receptor (CAR) for cancer cells - by enabling the stable integration of the CAR gene. This method enhances the technique of producing CAR-T cells to enable enhanced targeting of cancers for treatment.

Check the application of G4S in CAR-T Cell Preparation-Lentivirus Packaging


pdfCOApdfDatasheet

Order information


Catalog No. Product Name Size Price(In USD)
GMLS-Tag003-Ab01-PE200 Anti-G4S mAb(PE) 200T $1,188.00
GMLS-Tag003-Ab01-FITC200 Anti-G4S mAb(FITC) 200T $1,188.00
GMLS-Tag003-Ab01-APC200 Anti-G4S mAb(APC) 200T $1,188.00
GMLS-Tag003-Ab01-HRP200 Anti-G4S mAb(HRP) 200ul $713.00
GMLS-Tag003-Ab01 Anti-G4S rabbit monoclonal antibody (mAb) 1 mg

Size： 1mg | 10mg | 100mg


Description


Anti-G4S Rabbit monoclonal antibody (mAb)

Cat No. GMLS-Tag003-Ab01, GMLS-Tag003-Ab01-PE200, GMLS-Tag003-Ab01-FITC200, GMLS-Tag003-Ab01-APC200, GMLS-Tag003-Ab01-HRP200
Product Name Anti-G4S Rabbit monoclonal antibody (mAb)
Target G4S
Expression platform mammalian cell
Isotypes Rabbit IgG1
Bioactivity validation G4S binding, Competitive immunoassay validation (Competitive ELISA) in G4S level test.
Tag Rabbit Fc
Products description Anti-G4S monoclonal antibody is expressed from mammalian cell.
Species Rabbit
Conjugate Null/PE/FIT/APC/HRP
Purity Purity: ≥95% (SDS-PAGE)
Application Competitive immunoassay validation (Competitive ELISA) and other Immunoassay, PK & PD assay for G4S payload of Antibody-drug Conjugate (ADC).
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Validation Data


    FMC64 and G4S Linker antibody validation

    Figure 1. The GTU-ADA-FMC63-Ab01 and GMLS-Tag003-Ab-1 are validated to detect CAR-NK cells.

    G4S Linker antibody validation

    Figure 2. For detecting CAR-T cells, GeneMedi’s GMLS-Tag003-Ab-1 detection background is lower, and the detection results are closer to specific antigen detection, compared to Company C.


    Click to get more Data / Case study about the product.



    Associated products

    Category Cat No. Products Name
    CAR Detection Antibody GMLS-Tag003-Ab01 Anti-G4S monoclonal antibody (mAb)
    CAR Detection Antibody GTU-ADA-FMC63-Ab01~06 Anti-FMC63 monoclonal antibody (mAb)
    CAR Detection Antibody GMLS-Tag002-Ab01 Anti-VHH monoclonal antibody (mAb)