Anti-Exatecan (Exatecan Mesylate) monoclonal antibody (mAb)

Anti-Exatecan monoclonal antibody (mAb) for ADC is designed and developed for selective cancer therapy, targeting Exatecan Mesylate, a topoisomerase I inhibitor, to cancer cells. Exatecan binds and inhibits topoisomerase I, which is involved in DNA replication and causes cancer cells to die without affecting other cells.

Check the application of Exatecan Mesylate (Exatecan) in ADCs


pdfMSDSpdfCOApdfDatasheet

Order information


Catalog No.Product NameSizePrice(In USD)
GTU-Bios-Exatecan-Ab-1Anti-Exatecan (Exatecan Mesylate) human monoclonal antibody (mAb)1mg1690
GTU-Bios-Exatecan-Ab-2Anti-Exatecan (Exatecan Mesylate) mouse monoclonal antibody (mAb)1mg1690
GTU-Bios-Exatecan-Ab-3Anti-Exatecan (Exatecan Mesylate) mouse monoclonal antibody (mAb)1mg1690

Size： 1mg | 10mg | 100mg


Description


Anti-Exatecan (Exatecan Mesylate) human monoclonal antibody (mAb)

Cat No.GTU-Bios-Exatecan-Ab-1
Product NameAnti-Exatecan (Exatecan Mesylate) human monoclonal antibody (mAb)
TargetExatecan Mesylate (Exatecan)
Expression platformmammalian cell
IsotypesHuman IgG1
Bioactivity validationExatecan Mesylate (Exatecan) binding, Competitive immunoassay validation (Competitive ELISA) in Exatecan Mesylate (Exatecan) level test.
TaghFc
Products descriptionAnti-Exatecan Mesylate (Exatecan) monoclonal antibody is expressed from mammalian cell.
SpeciesHuman
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCompetitive immunoassay validation (Competitive ELISA) and other Immunoassay, PK & PD assay for Exatecan payload of Antibody-drug Conjugate (ADC).
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Anti-Exatecan (Exatecan Mesylate) mouse monoclonal antibody (mAb)

Cat No.GTU-Bios-Exatecan-Ab-2, GTU-Bios-Exatecan-Ab-3
Product NameAnti-Exatecan (Exatecan Mesylate) mouse monoclonal antibody (mAb)
TargetExatecan Mesylate (Exatecan)
Expression platformmammalian cell
IsotypesMouse IgG
Bioactivity validationExatecan Mesylate (Exatecan) binding, Competitive immunoassay validation (Competitive ELISA) in Exatecan Mesylate (Exatecan) level test.
TagmFc
Products descriptionAnti-Exatecan Mesylate (Exatecan)) mouse monoclonal antibody (mAb) is expressed from mammalian cell.
SpeciesMouse
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCompetitive immunoassay validation (Competitive ELISA) and other Immunoassay, PK & PD assay for Exatecan payload of Antibody-drug Conjugate (ADC).
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Validation Data


    Click to get more Data / Case study about the product.



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