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AAV-PHP.eB Rep-Cap plasmid (specific serotype across (blood-brain barrier(BBB) AAV RC plamid) (Amp and Kanamycin) (GeneMedi Owned)
GeneMedi's AAV-PHP.eB Rep-Cap plasmid supplies the AAV2 Rep (replication) proteins and the AAV-PHP.eB capsid protein.
You can produce AAV-PHP.eB particle in 293T cell line in high titer using GeneMedi's AAV-PHP.eB Rep-Cap plasmid with GM's AAV expression vector (overexpression or shRNA) and AAV helper plasmid.
With the blood-brain barrier(BBB) crossing propertiy, AAV-PHP.B shows potential applications in CNS (neuron) gene therapy, especially in neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD), or neurogenetic disease such as Spinal Muscular Atrophy (SMA) and Huntington's disease(HD).
GeneMedi offers both Ampicillin (Amp) resistance and Kanamycin (Kan) resistance for the AAV Rep-Cap Plasmids.
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Product Description
| Cat.NO | Product Name | Organization Type | Price(In USD) | ||
|---|---|---|---|---|---|
| P-RC20 | AAV-PHP.eB Rep-Cap Plasmid (Amp resistance) Size：5ug | Academic | 1719 | ||
| P-RC20 | AAV-PHP.eB Rep-Cap Plasmid (Amp resistance) Size：5ug | Biotech & Pharma & Medical Device & Diagnostics | |||
| P-RC20 | AAV-PHP.eB Rep-Cap Plasmid (Amp resistance) Size：5ug | CRO&CDMO& CXO&CMC& Manufacturing company |
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| P-RC20 | AAV-PHP.eB Rep-Cap Plasmid (Amp resistance) Size：≥10mg |
All | |||
| P-RC20-Kan | AAV-PHP.eB Rep-Cap Plasmid (Kan resistance) Size：≥10mg |
All | |||
| P-PK20 | AAV-PHP.eB Vector
System (Amp resistance)
1. AAV-PHP.eB Rep-Cap Plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug |
Academic | 3024 | ||
| P-PK20 | AAV-PHP.eB Vector
System (Amp resistance)
1. AAV-PHP.eB Rep-Cap Plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug | Biotech & Pharma & Medical Device & Diagnostics | |||
| P-PK20 | AAV-PHP.eB Vector
System (Amp resistance)
1. AAV-PHP.eB Rep-Cap Plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug | CRO&CDMO& CXO&CMC& Manufacturing company |
|||
| P-PK20 | AAV-PHP.eB Vector
System (Amp resistance)
1. AAV-PHP.eB Rep-Cap Plasmid, ≥10mg 2. AAV Helper Plasmid, ≥10mg 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01-Kan), ≥10mg |
All | |||
| P-PK20-Kan | AAV-PHP.eB Vector
System(Kan resistance)
1. AAV-PHP.eB Rep-Cap Plasmid(Kan resistance), ≥10mg 2. AAV Helper Plasmid(Kan resistance), ≥10mg 3. pGMAAV-CMV-MCS-T2A-ZsGreen (Kan resistance) (P-AAVV-B01-Kan), ≥10mg |
All | |||
|
GeneMedi offers both seed and amplification services for the Amp-resistant AAV Rep-Cap Plasmid. GeneMedi only offers amplification services and do not provide seed for the Kan-resistant AAV Rep-Cap Plasmid currently. |
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| If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service. | |||||
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Terms of sale: For Seed (5ug): The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for any other party. For plasmid production& amplification (≥10mg): The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for themselves or any other party. |
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Citation
| Title | Publication | Date |
|---|---|---|
| Eosinophils promote pulmonary matrix destruction and emphysema via Cathepsin L | Signal Transduction and Targeted Therapy | 2023/10/11 |
| The circRNA circSEPT9 mediated by E2F1 and EIF4A3 facilitates the carcinogenesis and development of triple-negative breast cancer | Molecular Cancer | 2020/3/12 |
| Brown adipose tissue-derived Nrg4 alleviates endothelial inflammation and atherosclerosis in male mice | Nature Metabolism | 2022/11/18 |
| Targeting the transcription factor HES1 by L-menthol restores protein phosphatase 6 in keratinocytes in models of psoriasis | Nature Communications | 2022/12/19 |
| Ciliary Type III Adenylyl Cyclase in the VMH Is Crucial for High-Fat Diet-Induced Obesity Mediated by Autophagy | Advanced science | 2021/11/16 |
| The E3 ubiquitin ligase HUWE1 acts through the N-Myc-DLL1-NOTCH1 signaling axis to suppress glioblastoma progression | Cancer communications | 2022/7/18 |
| Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects | Acta Pharmaceutica Sinica B | 2022/12/14 |
| Microneedle-mediated gene delivery for the treatment of ischemic myocardial disease | Sci Adv | 2020/6/29 |
| Palmitoylation of PKCδ by ZDHHC5 in hypothalamic microglia presents as a therapeutic target for fatty liver disease | Theranostics | 2024/1/1 |
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Associated products and services
| Products & Service | Products & Service Information |
|---|---|
| AAV Packaging service | Detail |
| Promise-ORF™ viral CDNA library | Detail |
| Plasmid DNA Rapid Preparation Service | Detail |
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