AAV-LK03 vector system (AAV-LK03 expression system, AAV-LK03 packaging plasmid system)

GeneMedi (GM) AAV-LK03 Vector system is including: 1) AAV-LK03 Rep-Cap plasmid (AAV-LK03-RC plasmid) 2) AAV Helper plasmid 3) AAV expression vectors (overexpression or shRNA).

You can produce AAV-LK03 particle in 293T cell line in high titer using GeneMedi's AAV-LK03 Rep-Cap plasmid with GM's AAV expression vector (overexpression or shRNA) and AAV helper plasmid.

AAV-LK03 is a capsid variant of the adeno-associated virus (AAV) designed to improve liver transduction. It is primarily liver-tropic, making it an excellent candidate for liver-directed gene therapy. Studies have shown that AAV-LK03 offers enhanced transduction efficiency in human hepatocytes compared to other AAV serotypes, such as AAV2 and AAV8. It retains some tropism for other tissues but is largely focused on the liver.

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Product Description

Cat.NO Product Name Organization Type Price(In USD)
P-PK38 AAV-LK03 Vector System (Amp resistance)
1. AAV-LK03 Rep-Cap Plasmid, 5ug
2. AAV Helper Plasmid, 5ug
3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug
Academic 3379
P-PK38 AAV-LK03 Vector System (Amp resistance)
1. AAV-LK03 Rep-Cap Plasmid, 5ug
2. AAV Helper Plasmid, 5ug
3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug
Biotech & Pharma & Medical Device & Diagnostics
P-PK38 AAV-LK03 Vector System (Amp resistance)
1. AAV-LK03 Rep-Cap Plasmid, 5ug
2. AAV Helper Plasmid, 5ug
3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug
CRO&CDMO&
CXO&CMC&
Manufacturing company
P-PK38 AAV-LK03 Vector System (Amp resistance)
1. AAV-LK03 Rep-Cap Plasmid, ≥10mg
2. AAV Helper Plasmid, ≥10mg
3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01-Kan), ≥10mg
 All
P-PK38-Kan AAV-LK03 Vector System (Kan resistance)
1. AAV-LK03 Rep-Cap Plasmid (Kan resistance) , ≥10mg
2. AAV Helper Plasmid (Kan resistance) , ≥10mg
3. pGMAAV-CMV-MCS-T2A-ZsGreen (Kan resistance) (P-AAVV-B01-Kan), ≥10mg
 All
P-RC38 AAV-LK03 Rep-Cap Plasmid (Amp resistance)
Size：5ug 		Academic 2062
P-RC38 AAV-LK03 Rep-Cap Plasmid (Amp resistance)
Size：5ug 		Biotech & Pharma & Medical Device & Diagnostics
P-RC38 AAV-LK03 Rep-Cap Plasmid (Amp resistance)
Size：5ug 		CRO&CDMO&
CXO&CMC&
Manufacturing company
P-RC38 AAV-LK03 Rep-Cap Plasmid (Amp resistance)
Size：≥10mg 		All
P-RC38-Kan AAV-LK03 Rep-Cap Plasmid(Kan resistance)
Size：≥10mg 		All
GeneMedi offers both seed and amplification services for the Amp-resistant AAV Vector System.
GeneMedi only offers amplification services and do not provide seed for the Kan-resistant AAV Vector System currently.
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.
Terms of sale:
For Seed (5ug):
The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for any other party.

For plasmid production& amplification (≥10mg):
The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for themselves or any other party.

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