AAV-MyoAAV 4E vector system (AAV-MyoAAV 4E expression system, AAV-MyoAAV 4E packaging plasmid system) (Amp and Kanamycin) (GeneMedi Owned)

GeneMedi (GM) AAV-MyoAAV 4E Vector system is including: 1) AAV-MyoAAV 4E Rep-Cap plasmid (AAV-MyoAAV 4E-RC plasmid) 2) AAV Helper plasmid 3) AAV expression vectors (overexpression or shRNA).

You can produce AAV-MyoAAV 4E particle in 293T cell line in high titer using GeneMedi's AAV-MyoAAV 4E Rep-Cap plasmid with GM's AAV expression vector (overexpression or shRNA) and AAV helper plasmid.

MyoAAV4E can be considered as a new evolutionary form of MyoAAV4A with possible overloading of the properties, for example, enshrine improved characteristics, including transduction efficiency, uptake to specific muscle tissue or reduced sensitivity to the immune system. This variant might employ both capsid alterations and distinct promoter/enhancer motifs to deliver genes and accomplish transcription solely in muscle cells.

GeneMedi offers both Ampicillin (Amp) resistance and Kanamycin (Kan) resistance for the AAV Rep-Cap Plasmids, AAV expression Plasmids and AAV helper Plasmid.

Target products collectionGo to AAV vector system >>


Product Description

Cat.NO Product Name Organization Type Price(In USD)
P-PK34 AAV-MyoAAV 4E Vector System (Amp resistance)
1. MyoAAV 4E Rep-Cap Plasmid, 5ug
2. AAV Helper Plasmid, 5ug
3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug
Academic 3379
P-PK34 AAV-MyoAAV 4E Vector System (Amp resistance)
1. MyoAAV 4E Rep-Cap Plasmid, 5ug
2. AAV Helper Plasmid, 5ug
3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug
Industry R&D
(excluding
CRO&CDMO&CXO)
P-PK34 AAV-MyoAAV 4E Vector System (Amp resistance)
1. MyoAAV 4E Rep-Cap Plasmid, 5ug
2. AAV Helper Plasmid, 5ug
3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug
CRO&CDMO&
CXO&CMC&
Manufacturing company
P-PK34 AAV-MyoAAV 4E Vector System (Amp resistance)
1. MyoAAV 4E Rep-Cap Plasmid, ≥10mg
2. AAV Helper Plasmid, ≥10mg
3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01-Kan), ≥10mg
All
P-PK34-Kan AAV-MyoAAV 4E Vector System (Kan resistance)
1. MyoAAV 4E Rep-Cap Plasmid (Kan resistance) , ≥10mg
2. AAV Helper Plasmid (Kan resistance) , ≥10mg
3. pGMAAV-CMV-MCS-T2A-ZsGreen (Kan resistance) (P-AAVV-B01-Kan), ≥10mg
All
P-RC34 AAV-MyoAAV 4E Rep-Cap Plasmid (Amp resistance)
Size:5ug
Academic 2062
P-RC34 AAV-MyoAAV 4E Rep-Cap Plasmid (Amp resistance)
Size:5ug
Industry R&D
(excluding
CRO&CDMO&CXO)
P-RC34 AAV-MyoAAV 4E Rep-Cap Plasmid (Amp resistance)
Size:5ug
CRO&CDMO&
CXO&CMC&
Manufacturing company
P-RC34 AAV-MyoAAV 4E Rep-Cap Plasmid (Amp resistance)
Size:≥10mg
All
P-RC34-Kan AAV-MyoAAV 4E Rep-Cap Plasmid(Kan resistance)
Size:≥10mg
All
GeneMedi offers both seed and amplification services for the Amp-resistant AAV Vector System.
GeneMedi only offers amplification services and do not provide seed for the Kan-resistant AAV Vector System currently.
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.
Terms of sale:
For Seed (5ug):
The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for any other party.

For plasmid production& amplification (≥10mg):
The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for themselves or any other party.

Citation

Title Publication Date
[PDF] Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis Cell Metabolism 2023/10/3
LITTIP/Lgr6/HnRNPK complex regulates cementogenesis via Wnt signaling International Journal of Oral Science 2023/8/9
Targeted Delivery of RGD-CD146+CD271+ Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Promotes Blood-Spinal Cord Barrier Repair after Spinal Cord Injury ACS Nano 2023/9/11
Adipocyte-Derived Exosomal MTTP Suppresses Ferroptosis and Promotes Chemoresistance in Colorectal Cancer Advanced Science 2022/8/17
Akt-mediated mitochondrial metabolism regulates proplatelet formation and platelet shedding post vasopressin exposure Journal of Thrombosis and Haemostasis 2022/12/22
CLN7 is an organellar chloride channel regulating lysosomal function Science advances 2021/12/15
Allosteric Regulation of IGF2BP1 as a Novel Strategy for the Activation of Tumor Immune Microenvironment ACS Central Science 2022/5/17
Poly(I:C) preconditioning protects the heart against myocardial ischemia/reperfusion injury through TLR3/PI3K/Akt-dependent pathway Signal Transduct Target Ther 2020/11/6
WTAP-mediated m6A modification of FRZB triggers the inflammatory response via the Wnt signaling pathway in osteoarthritis Experimental & Molecular Medicine 2024/1/4
MicroRNA-375 is a therapeutic target for castration-resistant prostate cancer through the PTPN4/STAT3 axis Experimental & Molecular Medicine 2022/8/30


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Associated products and services


Products & Service Products & Service Information
AAV Packaging service Detail
Promise-ORF™ viral CDNA library Detail
Plasmid DNA Rapid Preparation Service Detail