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AAV-AAV4 vector system (AAV-AAV4 expression system, AAV-AAV4 packaging plasmid system) (Amp and Kanamycin) (GeneMedi Owned)
GeneMedi (GM) AAV4 Vector system is including: 1) AAV4 Rep-Cap plasmid (AAV4-RC plasmid) 2) AAV Helper plasmid 3) AAV expression vectors (overexpression or shRNA).
You can produce AAV4 particle in 293T cell line in high titer using GeneMedi's AAV4 Rep-Cap plasmid with GM's AAV expression vector (overexpression or shRNA) and AAV helper plasmid.
The tissue tropism of AAV4 vector has been validated in lung and heart, as well as low transduction efficiency and viral genome copy numbers in the liver, with potential applications in tissue-specific gene therapy.
GeneMedi offers both Ampicillin (Amp) resistance and Kanamycin (Kan) resistance for the AAV Rep-Cap Plasmids, AAV expression Plasmids and AAV helper Plasmid.
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Product Description
| Cat.NO | Product Name | Organization Type | Price(In USD) | ||
|---|---|---|---|---|---|
| P-PK27 | AAV-VEC Vector System (Amp resistance) 1. AAV4 Rep-Cap Plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug | Academic | 3379 | ||
| P-PK27 | AAV-VEC Vector System (Amp resistance) 1. AAV4 Rep-Cap Plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug | Biotech & Pharma & Medical Device & Diagnostics | |||
| P-PK27 | AAV-VEC Vector System (Amp resistance) 1. AAV4 Rep-Cap Plasmid, 5ug 2. AAV Helper Plasmid, 5ug 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug | CRO&CDMO& CXO&CMC& Manufacturing company |
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| P-PK27 | AAV-VEC Vector System (Amp resistance) 1. AAV4 Rep-Cap Plasmid, ≥10mg 2. AAV Helper Plasmid, ≥10mg 3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01-Kan), ≥10mg |
All | |||
| P-PK27-Kan | AAV-VEC Vector System (Kan resistance) 1. AAV4 Rep-Cap Plasmid (Kan resistance) , ≥10mg 2. AAV Helper Plasmid (Kan resistance) , ≥10mg 3. pGMAAV-CMV-MCS-T2A-ZsGreen (Kan resistance) (P-AAVV-B01-Kan), ≥10mg |
All | |||
| P-RC27 | AAV-VEC Rep-Cap
Plasmid (Amp resistance)
Size：5ug |
Academic | 2062 | ||
| P-RC27 | AAV-VEC Rep-Cap
Plasmid (Amp resistance)
Size：5ug | Biotech & Pharma & Medical Device & Diagnostics | |||
| P-RC27 | AAV-VEC Rep-Cap
Plasmid (Amp resistance)
Size：5ug | CRO&CDMO& CXO&CMC& Manufacturing company |
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| P-RC27 | AAV-VEC Rep-Cap
Plasmid (Amp resistance)
Size：≥10mg |
All | |||
| P-RC27-Kan | AAV-VEC Rep-Cap
Plasmid(Kan resistance)
Size：≥10mg |
All | |||
|
GeneMedi offers both seed and amplification services for the Amp-resistant AAV Vector System. GeneMedi only offers amplification services and do not provide seed for the Kan-resistant AAV Vector System currently. |
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| If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service. | |||||
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Terms of sale: For Seed (5ug): The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for any other party. For plasmid production& amplification (≥10mg): The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for themselves or any other party. |
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Citation
| Title | Publication | Date |
|---|---|---|
| HDAC1/2/3 are major histone desuccinylases critical for promoter desuccinylation | Cell Discovery | 2023/8/15 |
| Chimeric antigen receptor-modified macrophages ameliorate liver fibrosis in preclinical models | Journal of Hepatology | 2024/2/8 |
| Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax | Kidney International | 2022/9/8 |
| CD8 T Cell-Derived Exosomal miR-186-5p Elicits Renal Inflammation via Activating Tubular TLR7/8 Signal Axis | Advanced Science | 2023/7/3 |
| Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence | Nature Communications | 2024/2/16 |
| Intestinal dysbiosis exacerbates susceptibility to the anti-NMDA receptor encephalitis-like phenotype by changing blood brain barrier permeability and immune homeostasis | Brain, Behavior, and Immunity | 2023/11/27 |
| SIRT6 protects vascular smooth muscle cell from osteogenic transdifferentiation via Runx2 in chronic kidney disease | Journal of Clinical Investigation | 2021/11/18 |
| Therapeutic reversal of Huntington's disease by in vivo self-assembled siRNAs | BRAIN | 2021/12/15 |
| NLRC3 Expression in Macrophage Impairs Glycolysis and Host Immune Defence by Modulating the NF-κB-NFAT5 Complex During Sepsis-induced Immunosuppression | Molecular Therapy | 2022/9/6 |
| Hepatic HuR modulates lipid homeostasis in response to high-fat diet | Nature Communications | 2020/6/16 |
Validation data
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Associated products and services
| Products & Service | Products & Service Information |
|---|---|
| AAV Packaging service | Detail |
| Promise-ORF™ viral CDNA library | Detail |
| Plasmid DNA Rapid Preparation Service | Detail |
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