AAV2 variant (Y272F, Y444F, Y500F, Y730F) vector system (retina-validated AAV expression and packaging plasmids) (Amp and Kanamycin) (GeneMedi Owned)

GeneMedi (GM) AAV2 variant (Y272F, Y444F, Y500F, Y730F) Vector system is including: 1) AAV2 variant (Y272F, Y444F, Y500F, Y730F) Rep-Cap plasmid (AAV2 variant (Y272F, Y444F, Y500F, Y730F)-RC plasmid) 2) AAV Helper plasmid 3) AAV expression vectors (overexpression or shRNA).

You can produce AAV2 variant (Y272F, Y444F, Y500F, Y730F) particle in 293T cell line in high titer using GeneMedi's AAV2 variant (Y272F, Y444F, Y500F, Y730F) Rep-Cap plasmid with GM's AAV expression vector (overexpression or shRNA) and AAV helper plasmid.

The tissue tropism of AAV2 variant (Y272F, Y444F, Y500F, Y730F) vector has been validated in retina (retinal ganglion cells) by both intravitreal injection and sub-retinal injection., with potential applications in retina gene therapy.

GeneMedi offers both Ampicillin (Amp) resistance and Kanamycin (Kan) resistance for the AAV Rep-Cap Plasmids, AAV expression Plasmids and AAV helper Plasmid.

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Product Description

Cat.NO Product Name Organization Type Price(In USD)
P-PK04 AAV2 variant(Y444F)Vector System (Amp resistance)
1. AAV2 variant (Y272F, Y444F, Y500F, Y730F) Rep-Cap Plasmid, 5ug
2. AAV Helper Plasmid, 5ug
3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug
Academic 3024
P-PK04 AAV2 variant(Y444F)Vector System (Amp resistance)
1. AAV2 variant (Y272F, Y444F, Y500F, Y730F) Rep-Cap Plasmid, 5ug
2. AAV Helper Plasmid, 5ug
3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug
Industry R&D
(excluding
CRO&CDMO&CXO)
P-PK04 AAV2 variant(Y444F)Vector System (Amp resistance)
1. AAV2 variant (Y272F, Y444F, Y500F, Y730F) Rep-Cap Plasmid, 5ug
2. AAV Helper Plasmid, 5ug
3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01), 5ug
CRO&CDMO&
CXO&CMC&
Manufacturing company
P-PK04 AAV2 variant(Y444F)Vector System (Amp resistance)
1. AAV2 variant (Y272F, Y444F, Y500F, Y730F) Rep-Cap Plasmid, ≥10mg
2. AAV Helper Plasmid, ≥10mg
3. pGMAAV-CMV-MCS-T2A-ZsGreen (P-AAVV-B01-Kan), ≥10mg
 All
P-PK04-Kan AAV2 variant(Y444F)Vector System (Kan resistance)
1. AAV2 variant (Y272F, Y444F, Y500F, Y730F) Rep-Cap Plasmid (Kan resistance) , ≥10mg
2. AAV Helper Plasmid (Kan resistance) , ≥10mg
3. pGMAAV-CMV-MCS-T2A-ZsGreen (Kan resistance) (P-AAVV-B01-Kan), ≥10mg
 All
P-RC04 AAV2 variant(Y444F)Rep-Cap Plasmid (Amp resistance)
Size：5ug 		Academic 1719
P-RC04 AAV2 variant(Y444F)Rep-Cap Plasmid (Amp resistance)
Size：5ug 		Industry R&D
(excluding
CRO&CDMO&CXO)
P-RC04 AAV2 variant(Y444F)Rep-Cap Plasmid (Amp resistance)
Size：5ug 		CRO&CDMO&
CXO&CMC&
Manufacturing company
P-RC04 AAV2 variant(Y444F)Rep-Cap Plasmid (Amp resistance)
Size：≥10mg 		All
P-RC04-Kan AAV2 variant(Y444F)Rep-Cap Plasmid(Kan resistance)
Size：≥10mg 		All
GeneMedi offers both seed and amplification services for the Amp-resistant AAV Vector System.
GeneMedi only offers amplification services and do not provide seed for the Kan-resistant AAV Vector System currently.
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.
Terms of sale:
For Seed (5ug):
The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for any other party.

For plasmid production& amplification (≥10mg):
The purchaser may not reverse engineer this product to extract the sequence for independent use. The purchaser may not transfer this product to others for manufacturing purposes. The purchaser may not use this material to manufacture this product for themselves or any other party.

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