SERPINB2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of SERPINB2. The page also collects GeneMedi's different modalities and formats products for SERPINB2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the SERPINB2 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

Target IDGM-TA086
Target NameSERPINB2
Gene ID5055,18788,60325,701805,609604,101085412,505184,100051584
Gene Symbol and SynonymsHsT1201,ovalbumin,PAI,PAI-2,PAI2,Pai2a,PLANH2,SERPINB2
Uniprot AccessionP05120,P29524
Uniprot Entry NamePAI2_HUMAN,PAI2_RAT
Protein Sub-locationTransmembrane Protein
CategoryTherapeutics Target
DiseaseCancer
Gene EnsemblENSG00000197632
Target ClassificationTumor-associated antigen (TAA)


Pre-made anti-SERPINB2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-SERPINB2 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-SERPINB2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-SERPINB2 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail



Multi-species PAI2/ SERPINB2/ HsT1201 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SERPINB2 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
SERPINB2 VLP (virus-like particle)Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellProducts Developing



Pre-made SERPINB2 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMLP004001human SERPINB2 Lentivirus plasmidBC012609HumanLentivirus plasmidDetail
vGMLP004001human SERPINB2 Lentivirus particleBC012609HumanLentivirus particleDetail
vGMLP003666human SERPINB2 Lentivirus particleNM_001143818HumanLentivirus particleDetail
pGMLP003666human SERPINB2 Lentivirus plasmidNM_001143818HumanLentivirus plasmidDetail
pGMLPm002042mouse Serpinb2 Lentivirus plasmidNM_011111MouseLentivirus plasmidDetail
vGMLPm002042mouse Serpinb2 Lentivirus particleNM_011111MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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