AKT2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of AKT2. The page also collects GeneMedi's different modalities and formats products for AKT2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the AKT2 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The gene serves as an oncogene in the tumorigenesis of cancer cells For example, its overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins, and has also been implicated in insulin signaling. [provided by RefSeq, Nov 2019]
Target ID | GM-T94621 |
Target Name | AKT2 |
Gene ID | 208,11652,25233,700591,449021,100499544,534923,100064671 |
Gene Symbol and Synonyms | 2410016A19Rik,AKT2,HIHGHH,PKB,PKBB,PKBBETA,PRKBB,RAC-BETA |
Uniprot Accession | P31751,P47197 |
Uniprot Entry Name | AKT2_HUMAN,AKT2_RAT |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Cancer |
Gene Ensembl | ENSG00000105221 |
Target Classification | Kinase, Tumor-associated antigen (TAA) |
Pre-made anti-AKT2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-AKT2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-AKT2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-AKT2 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species AKT2/ HIHGHH/ PKBB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AKT2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
AKT2 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made AKT2 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMLV000359 | human AKT2 Lentivirus plasmid | NM_001243027.2 | Human | Lentivirus plasmid | Detail |
vGMLV000359 | human AKT2 Lentivirus particle | NM_001243027.2 | Human | Lentivirus particle | Detail |
pGMAD000122 | mouse Akt2 Adenovirus plasmid | NM_001331108.1 | Mouse | Adenovirus plasmid | Detail |
pGMAD000436 | house mouse Akt2 Adenovirus plasmid | NM_001331108.1 | House Mouse | Adenovirus plasmid | Detail |
pGMAAV000144 | mouse Akt2 AAV plasmid | NM_001110208 | Mouse | AAV plasmid | Detail |
pGMAAV000152 | mouse Akt2 AAV plasmid | NM_001331108.1 | Mouse | AAV plasmid | Detail |
vGMAD000122 | mouse Akt2 Adenovirus particle | NM_001331108.1 | Mouse | Adenovirus particle | Detail |
vGMAD000436 | house mouse Akt2 Adenovirus particle | NM_001331108.1 | House Mouse | Adenovirus particle | Detail |
vGMAAV000144 | mouse Akt2 AAV particle | NM_001110208 | Mouse | AAV particle | Detail |
vGMAAV000152 | mouse Akt2 AAV particle | NM_001331108.1 | Mouse | AAV particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.