AKT2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of AKT2. The page also collects GeneMedi's different modalities and formats products for AKT2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the AKT2 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The gene serves as an oncogene in the tumorigenesis of cancer cells For example, its overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins, and has also been implicated in insulin signaling. [provided by RefSeq, Nov 2019]

Target IDGM-T94621
Target NameAKT2
Gene ID208,11652,25233,700591,449021,100499544,534923,100064671
Gene Symbol and Synonyms2410016A19Rik,AKT2,HIHGHH,PKB,PKBB,PKBBETA,PRKBB,RAC-BETA
Uniprot AccessionP31751,P47197
Uniprot Entry NameAKT2_HUMAN,AKT2_RAT
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target
DiseaseCancer
Gene EnsemblENSG00000105221
Target ClassificationKinase, Tumor-associated antigen (TAA)


Pre-made anti-AKT2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-AKT2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-AKT2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-AKT2 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabTherapeutics Target antibodyDetail



Recombinant multi-species AKT2/ HIHGHH/ PKBB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AKT2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
AKT2 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made AKT2 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMLV000359human AKT2 Lentivirus plasmidNM_001243027.2HumanLentivirus plasmidDetail
vGMLV000359human AKT2 Lentivirus particleNM_001243027.2HumanLentivirus particleDetail
pGMAD000122mouse Akt2 Adenovirus plasmidNM_001331108.1MouseAdenovirus plasmidDetail
pGMAD000436house mouse Akt2 Adenovirus plasmidNM_001331108.1House MouseAdenovirus plasmidDetail
pGMAAV000144mouse Akt2 AAV plasmidNM_001110208MouseAAV plasmidDetail
pGMAAV000152mouse Akt2 AAV plasmidNM_001331108.1MouseAAV plasmidDetail
vGMAD000122mouse Akt2 Adenovirus particleNM_001331108.1MouseAdenovirus particleDetail
vGMAD000436house mouse Akt2 Adenovirus particleNM_001331108.1House MouseAdenovirus particleDetail
vGMAAV000144mouse Akt2 AAV particleNM_001110208MouseAAV particleDetail
vGMAAV000152mouse Akt2 AAV particleNM_001331108.1MouseAAV particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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