CCN1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of CCN1. The page also collects GeneMedi's different modalities and formats products for CCN1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the CCN1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Secreted Protein/Potential Cytokines.
The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation. [provided by RefSeq, Sep 2011]
Target ID | GM-T56505 |
Target Name | CCN1 |
Gene ID | 3491,16007,83476,714970,479967,101100068,508941,100064066 |
Gene Symbol and Synonyms | CCN1,CYR61,GIG1,IGFBP10 |
Uniprot Accession | O00622,Q9ES72 |
Uniprot Entry Name | CCN1_HUMAN,CCN1_RAT |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target |
Disease | Cancer |
Gene Ensembl | ENSG00000142871 |
Target Classification | Tumor-associated antigen (TAA) |
Pre-made anti-CCN1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-CCN1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CCN1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-CCN1 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Recombinant multi-species CCN1/ CYR61/ GIG1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCN1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
CCN1 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made CCN1 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
vGMLP000491 | human CYR61 Lentivirus particle | NM_001554 | Human | Lentivirus particle | Detail |
pGMLP000491 | human CYR61 Lentivirus plasmid | NM_001554 | Human | Lentivirus plasmid | Detail |
vGMAP000008 | Human CYR61 Adenovirus particle | BC001271 | Human | Adenovirus particle | Detail |
pGMAP000008 | Human CYR61 Adenovirus plasmid | BC001271 | Human | Adenovirus plasmid | Detail |
pGMAD000547 | Norway rat Ccn1 Adenovirus plasmid | NM_031327.2 | Norway Rat | Adenovirus plasmid | Detail |
vGMAD000547 | Norway rat Ccn1 Adenovirus particle | NM_031327.2 | Norway Rat | Adenovirus particle | Detail |
pGMLPm002791 | mouse Cyr61 Lentivirus plasmid | NM_010516 | Mouse | Lentivirus plasmid | Detail |
vGMLPm002791 | mouse Cyr61 Lentivirus particle | NM_010516 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.