MYC: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of MYC. The page also collects GeneMedi's different modalities and formats products for MYC in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the MYC target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
Target ID | GM-T36121 |
Target Name | MYC |
Gene ID | 4609,17869,24577,694626,403924,100379628,511077,100068097 |
Gene Symbol and Synonyms | bHLHe39,c-Myc,CMYC,mMyc,MRTL,MYC,Myc2,MYCC,Niard,Nird,RNCMYC,v-myc |
Uniprot Accession | P01106,P09416,B8XIA5,Q28350,P68271,Q2HJ27 |
Uniprot Entry Name | MYC_HUMAN,MYC_MACMU,MYC_RAT,MYC_FELCA,MYC_CANLF,MYC_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Breast Cancer, Lung Cancer, Lung cancer |
Gene Ensembl | ENSG00000136997 |
Target Classification | N/A |
Pre-made anti-MYC inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-MYC monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-MYC mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-MYC monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species MYC/ MRTLC/ bHLHe39 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MYC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
MYC protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made MYC viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
vGMLV000287 | human MYC Lentivirus particle | NM_002467.5 | Human | Lentivirus particle | Detail |
vGMLV000614 | human MYC Lentivirus particle | NM_002467 | Human | Lentivirus particle | Detail |
pGMLV000614 | human MYC Lentivirus plasmid | NM_002467 | Human | Lentivirus plasmid | Detail |
pGMLV000288 | human MYC Lentivirus plasmid | NM_002467.4 | Human | Lentivirus plasmid | Detail |
pGMAP000557 | Human MYC Adenovirus plasmid | BC058901 | Human | Adenovirus plasmid | Detail |
pGMLV000287 | human MYC Lentivirus plasmid | NM_002467.5 | Human | Lentivirus plasmid | Detail |
vGMAP000557 | Human MYC Adenovirus particle | BC058901 | Human | Adenovirus particle | Detail |
vGMLV000288 | human MYC Lentivirus particle | NM_002467.4 | Human | Lentivirus particle | Detail |
pGMLV000144 | mouse Myc Lentivirus plasmid | NM_010849 | Mouse | Lentivirus plasmid | Detail |
pGMAD000083 | mouse Myc Adenovirus plasmid | NM_001177352.1 | Mouse | Adenovirus plasmid | Detail |
pGMAD000252 | rat Myc Adenovirus plasmid | NM_012603.2 | Rat | Adenovirus plasmid | Detail |
pGMAD000465 | Norway rat Myc Adenovirus plasmid | NM_012603.2 | Norway Rat | Adenovirus plasmid | Detail |
pGMAAV000056 | mouse Myc AAV plasmid | NM_010849.4 | Mouse | AAV plasmid | Detail |
vGMLV000144 | mouse Myc Lentivirus particle | NM_010849 | Mouse | Lentivirus particle | Detail |
vGMAD000083 | mouse Myc Adenovirus particle | NM_001177352.1 | Mouse | Adenovirus particle | Detail |
vGMAD000252 | rat Myc Adenovirus particle | NM_012603.2 | Rat | Adenovirus particle | Detail |
vGMAD000465 | Norway rat Myc Adenovirus particle | NM_012603.2 | Norway Rat | Adenovirus particle | Detail |
vGMAAV000056 | mouse Myc AAV particle | NM_010849.4 | Mouse | AAV particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
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