HTR2A: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of HTR2A. The page also collects GeneMedi's different modalities and formats products for HTR2A in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the HTR2A target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Target IDGM-T32060
Target NameHTR2A
Gene ID3356,15558,29595,613032,403882,101081108,407230,100009685
Gene Symbol and Synonyms5-HT-2,5-HT-2A,5-HT2A,5-HTR2A,5Ht-2,5HT2A,5HTR2A,E030013E04,Htr-2,HTR2,HTR2A
Uniprot AccessionP28223,P14842,P50128,O46635,Q75Z89
Uniprot Entry Name5HT2A_HUMAN,5HT2A_MACMU,5HT2A_RAT,5HT2A_CANLF,5HT2A_BOVIN
Protein Sub-locationTransmembrane Protein
CategoryTherapeutics Target
DiseaseSchizophrenia
Gene EnsemblENSG00000102468
Target ClassificationGPCR


Pre-made anti-HTR2A inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-HTR2A benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-HTR2A mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-HTR2A monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail



Multi-species 5HT2A/ HTR2A/ 5-HT2A VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HTR2A VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
HTR2A VLP (virus-like particle)Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellProducts Developing



Pre-made HTR2A viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMAP000503human HTR2A Adenovirus particleBC069356HumanAdenovirus particleDetail
pGMAP000503human HTR2A Adenovirus plasmidBC069356HumanAdenovirus plasmidDetail
pGMLP002120human HTR2A Lentivirus plasmidNM_000621HumanLentivirus plasmidDetail
vGMLP002120human HTR2A Lentivirus particleNM_000621HumanLentivirus particleDetail
pGMLPm002960mouse Htr2a Lentivirus plasmidNM_172812MouseLentivirus plasmidDetail
vGMLPm002960mouse Htr2a Lentivirus particleNM_172812MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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