SOX2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of SOX2. The page also collects GeneMedi's different modalities and formats products for SOX2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the SOX2 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]

Target IDGM-T00724
Target NameSOX2
Gene ID6657,20674,499593,707039,488092,100379629,784383,100146979
Gene Symbol and SynonymsANOP3,lcc,MCOPS3,RGD1565646,Sox-2,SOX2,ysb
Uniprot AccessionP48431
Uniprot Entry NameSOX2_HUMAN
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target
DiseaseLung Cancer
Gene EnsemblENSG00000181449
Target ClassificationN/A


Pre-made anti-SOX2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-SOX2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-SOX2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-SOX2 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabTherapeutics Target antibodyDetail



Recombinant multi-species SOX2/ ANOP3/ MCOPS3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOX2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
SOX2 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made SOX2 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLV000264human SOX2 Lentivirus particleNM_003106.2HumanLentivirus particleDetail
pGMAP000433Human SOX2 Adenovirus plasmidBC013923HumanAdenovirus plasmidDetail
pGMLV000263human SOX2 Lentivirus plasmidNM_003106.3HumanLentivirus plasmidDetail
vGMLV000263human SOX2 Lentivirus particleNM_003106.3HumanLentivirus particleDetail
vGMAP000433Human SOX2 Adenovirus particleBC013923HumanAdenovirus particleDetail
pGMLV000264human SOX2 Lentivirus plasmidNM_003106.2HumanLentivirus plasmidDetail
pGMAD000053rat Sox2 Adenovirus plasmidNM_001109181.1RatAdenovirus plasmidDetail
pGMLPm002981mouse Sox2 Lentivirus plasmidNM_011443.4MouseLentivirus plasmidDetail
vGMAD000053rat Sox2 Adenovirus particleNM_001109181.1RatAdenovirus particleDetail
vGMLPm002981mouse Sox2 Lentivirus particleNM_011443.4MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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