SOX2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of SOX2. The page also collects GeneMedi's different modalities and formats products for SOX2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the SOX2 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]
Target ID | GM-T00724 |
Target Name | SOX2 |
Gene ID | 6657,20674,499593,707039,488092,100379629,784383,100146979 |
Gene Symbol and Synonyms | ANOP3,lcc,MCOPS3,RGD1565646,Sox-2,SOX2,ysb |
Uniprot Accession | P48431 |
Uniprot Entry Name | SOX2_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Lung Cancer |
Gene Ensembl | ENSG00000181449 |
Target Classification | N/A |
Pre-made anti-SOX2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-SOX2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-SOX2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-SOX2 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species SOX2/ ANOP3/ MCOPS3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOX2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
SOX2 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made SOX2 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
vGMLV000264 | human SOX2 Lentivirus particle | NM_003106.2 | Human | Lentivirus particle | Detail |
pGMAP000433 | Human SOX2 Adenovirus plasmid | BC013923 | Human | Adenovirus plasmid | Detail |
pGMLV000263 | human SOX2 Lentivirus plasmid | NM_003106.3 | Human | Lentivirus plasmid | Detail |
vGMLV000263 | human SOX2 Lentivirus particle | NM_003106.3 | Human | Lentivirus particle | Detail |
vGMAP000433 | Human SOX2 Adenovirus particle | BC013923 | Human | Adenovirus particle | Detail |
pGMLV000264 | human SOX2 Lentivirus plasmid | NM_003106.2 | Human | Lentivirus plasmid | Detail |
pGMAD000053 | rat Sox2 Adenovirus plasmid | NM_001109181.1 | Rat | Adenovirus plasmid | Detail |
pGMLPm002981 | mouse Sox2 Lentivirus plasmid | NM_011443.4 | Mouse | Lentivirus plasmid | Detail |
vGMAD000053 | rat Sox2 Adenovirus particle | NM_001109181.1 | Rat | Adenovirus particle | Detail |
vGMLPm002981 | mouse Sox2 Lentivirus particle | NM_011443.4 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.