PLA2G16: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of PLA2G16. The page also collects GeneMedi's different modalities and formats products for PLA2G16 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the PLA2G16 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

Enables N-acyltransferase activity; phospholipase A1 activity; and phospholipase A2 activity. Involved in N-acylphosphatidylethanolamine metabolic process. Predicted to be located in several cellular components, including lysosome; nuclear envelope; and peroxisome. Predicted to be active in cytoplasm. Biomarker of seminoma. [provided by Alliance of Genome Resources, Apr 2022]

Target IDGM-MP1377
Target NamePLA2G16
Gene ID11145,225845,722178,476045,101090719
Gene Symbol and SynonymsAdPLA,H-REV107,H-REV107-1,HRASLS3,HREV107,HREV107-1,HREV107-3,HRSL3,MLP-3,PLA2G16,PLAAT-3,PLAAT3
Uniprot AccessionP53816
Uniprot Entry NamePLAT3_HUMAN
Protein Sub-locationTransmembrane Protein
Category
DiseaseCancer
Gene EnsemblENSG00000176485
Target ClassificationTumor-associated antigen (TAA)


Pre-made anti-PLA2G16 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-PLA2G16 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PLA2G16 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-PLA2G16 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional AntibodyDetail



Multi-species PLAT3/ PLA2G16/ AdPLA VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLA2G16 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
PLA2G16 VLP (virus-like particle)Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellProducts Developing



Pre-made PLA2G16 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMLP004244human PLA2G16 Lentivirus plasmidNM_007069HumanLentivirus plasmidDetail
vGMLP004244human PLA2G16 Lentivirus particleNM_007069HumanLentivirus particleDetail
pGMLPm003261mouse Pla2g16 Lentivirus plasmidNM_139269MouseLentivirus plasmidDetail
vGMLPm003261mouse Pla2g16 Lentivirus particleNM_139269MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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