PLA2G16: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of PLA2G16. The page also collects GeneMedi's different modalities and formats products for PLA2G16 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the PLA2G16 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
Enables N-acyltransferase activity; phospholipase A1 activity; and phospholipase A2 activity. Involved in N-acylphosphatidylethanolamine metabolic process. Predicted to be located in several cellular components, including lysosome; nuclear envelope; and peroxisome. Predicted to be active in cytoplasm. Biomarker of seminoma. [provided by Alliance of Genome Resources, Apr 2022]
Target ID | GM-MP1377 |
Target Name | PLA2G16 |
Gene ID | 11145,225845,722178,476045,101090719 |
Gene Symbol and Synonyms | AdPLA,H-REV107,H-REV107-1,HRASLS3,HREV107,HREV107-1,HREV107-3,HRSL3,MLP-3,PLA2G16,PLAAT-3,PLAAT3 |
Uniprot Accession | P53816 |
Uniprot Entry Name | PLAT3_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | Cancer |
Gene Ensembl | ENSG00000176485 |
Target Classification | Tumor-associated antigen (TAA) |
Pre-made anti-PLA2G16 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-PLA2G16 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PLA2G16 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-PLA2G16 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody | Detail |
Multi-species PLAT3/ PLA2G16/ AdPLA VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLA2G16 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
PLA2G16 VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made PLA2G16 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMLP004244 | human PLA2G16 Lentivirus plasmid | NM_007069 | Human | Lentivirus plasmid | Detail |
vGMLP004244 | human PLA2G16 Lentivirus particle | NM_007069 | Human | Lentivirus particle | Detail |
pGMLPm003261 | mouse Pla2g16 Lentivirus plasmid | NM_139269 | Mouse | Lentivirus plasmid | Detail |
vGMLPm003261 | mouse Pla2g16 Lentivirus particle | NM_139269 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.